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The MissingProteinPedia is a protein data and information sharing web system that aims to collate any relevant data ‘Missing proteins’ as defined by neXtProt. At its core is a schema-less database-driven web system allowing captures of all PE2-4 protein PubMed data, based on gene and protein including synonyms. The database also allows unpublished, preliminary or proprietary data (e.g., antibody, MS, cell biological and genetic studies) to be shared with collaborators via a protected interface.

MissingProteinPedia facilitates the Human Proteome Project (HPP) cross-disciplinary collaboration by providing a complimentary, unfiltered, lower stringency perspective to both the HPP metrics and guidelines approaches, enabling community evaluation and scrutiny. MissingProteinPedia incorporates text mining technology to fetch and search accumulated UniProt, GeneCards, GeneRifs, PubMed PE2-4 data. Besides, MissingProteinPedia summarizes publicly available MS data from PRIDE, GPMDB, ProteomicsDB and MaxQB for relevant PE2-4 proteins. It allows community administrators to curate information before web publication.

We encourage all visitors to browse and contribute to 'finding' these proteins by sharing any relevant information on them that we may have missed!


Showing 1-20 of 1,482 items.
Protein IDGene IDProtein NameChromosome IDGene NameTag(s) 
O00270GPR3112-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptorChromosome-612-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor
Q96PD6MOGAT12-acylglycerol O-acyltransferase 1Chromosome-22-acylglycerol O-acyltransferase 1
Q96P68OXGR12-oxoglutarate receptor 1Chromosome-132-oxoglutarate receptor 1
Q8TD47RPS4Y240S ribosomal protein S4, Y isoform 2Chromosome-Y40S ribosomal protein S4, Y isoform 2
P30939HTR1F5-hydroxytryptamine receptor 1FChromosome-35-hydroxytryptamine receptor 1F
P47898HTR5A5-hydroxytryptamine receptor 5AChromosome-75-hydroxytryptamine receptor 5A
Q8TE56ADAMTS17A disintegrin and metalloproteinase with thrombospondin motifs 17Chromosome-15A disintegrin and metalloproteinase with thrombospondin motifs 17
Q8TE59ADAMTS19A disintegrin and metalloproteinase with thrombospondin motifs 19Chromosome-5A disintegrin and metalloproteinase with thrombospondin motifs 19
P59510ADAMTS20A disintegrin and metalloproteinase with thrombospondin motifs 20Chromosome-12A disintegrin and metalloproteinase with thrombospondin motifs 20
Q9UKP5ADAMTS6A disintegrin and metalloproteinase with thrombospondin motifs 6Chromosome-5A disintegrin and metalloproteinase with thrombospondin motifs 6
Q7Z5M8ABHD12BAbhydrolase domain-containing protein 12BChromosome-14Abhydrolase domain-containing protein 12B
Q9H3Z7ABHD16BAbhydrolase domain-containing protein 16BChromosome-20Abhydrolase domain-containing protein 16B
Q9NQ33ASCL3Achaete-scute homolog 3Chromosome-11Achaete-scute homolog 3
Q8N0Z2ABRAActin-binding Rho-activating proteinChromosome-8Actin-binding Rho-activating protein
Q9C0K3ACTR3CActin-related protein 3CChromosome-7Actin-related protein 3C
Q7LC44ARCActivity-regulated cytoskeleton-associated proteinChromosome-8Activity-regulated cytoskeleton-associated protein
Q9NUZ1ACOXLAcyl-coenzyme A oxidase-like proteinChromosome-2Acyl-coenzyme A oxidase-like protein
P0C7M7ACSM4Acyl-coenzyme A synthetase ACSM4, mitochondrialChromosome-12Acyl-coenzyme A synthetase ACSM4, mitochondrial
P29275ADORA2BAdenosine receptor A2bChromosome-17Adenosine receptor A2b
P0DMS8ADORA3Adenosine receptor A3Chromosome-1Adenosine receptor A3

Related Publications

Publications to be cited for using MPP data and services

Islam, M.T. et al. Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the “Missing” Human Proteome. Journal of Proteome Research 13 (1), 76-83, doi: 10.1021/pr400794x (2014)
Islam, M.T. et al. A systematic bioinformatics approach to identify high quality MS data and functionally annotate proteins and proteomes. Methods Mol. Biol.1549, 163–176, doi: 10.1007/978-1-4939-6740-7_13 (2016)
Baker, M. S. et al. Accelerating the search for the missing proteins in the human proteome. Nat. Commun. 8, 14271 doi: 10.1038/ncomms14271 (2017).
Islam, M.T. et al. Missing ProteinPedia - under preparation.


Professor Mark S. Baker

  •  Department of Biomedical Sciences,

           Faculty of Medicine and Health Sciences,

           Level 1, 75 Talavera Rd, Macquarie University, NSW 2109, Australia

Bioinformatics, Database and Web Administration

Professor Shoba Ranganathan

  •  Department of Biomedical Sciences,

           Department of Chemistry and Biomolecular Science,

           Building F7B Room 121, Macquarie University, NSW 2109, Australia

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