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The MissingProteinPedia is a protein data and information sharing web system that aims to collate any relevant data ‘Missing proteins’ as defined by neXtProt. At its core is a schema-less database-driven web system allowing captures of all PE2-4 protein PubMed data, based on gene and protein including synonyms. The database also allows unpublished, preliminary or proprietary data (e.g., antibody, MS, cell biological and genetic studies) to be shared with collaborators via a protected interface.

MissingProteinPedia facilitates the Human Proteome Project (HPP) cross-disciplinary collaboration by providing a complimentary, unfiltered, lower stringency perspective to both the HPP metrics and guidelines approaches, enabling community evaluation and scrutiny. MissingProteinPedia incorporates text mining technology to fetch and search accumulated UniProt, GeneCards, GeneRifs, PubMed PE2-4 data. Besides, MissingProteinPedia summarizes publicly available MS data from PRIDE, GPMDB, ProteomicsDB and MaxQB for relevant PE2-4 proteins. It allows community administrators to curate information before web publication.

We encourage all visitors to browse and contribute to 'finding' these proteins by sharing any relevant information on them that we may have missed!


Showing 1-20 of 1,482 items.
Protein IDGene IDProtein NameChromosome IDGene NameTag(s) 
Q6P093AADACL2Arylacetamide deacetylase-like 2Chromosome-3Arylacetamide deacetylase-like 2
Q8WWZ4ABCA10ATP-binding cassette sub-family A member 10Chromosome-17ATP-binding cassette sub-family A member 10
Q9NSE7ABCC13Putative ATP-binding cassette sub-family C member 13Chromosome-21Putative ATP-binding cassette sub-family C member 13
Q7Z5M8ABHD12BAbhydrolase domain-containing protein 12BChromosome-14Abhydrolase domain-containing protein 12B
Q9H3Z7ABHD16BAbhydrolase domain-containing protein 16BChromosome-20Abhydrolase domain-containing protein 16B
Q8N0Z2ABRAActin-binding Rho-activating proteinChromosome-8Actin-binding Rho-activating protein
Q8TDN7ACER1Alkaline ceramidase 1Chromosome-19Alkaline ceramidase 1
Q9NUZ1ACOXLAcyl-coenzyme A oxidase-like proteinChromosome-2Acyl-coenzyme A oxidase-like protein
P0C7M7ACSM4Acyl-coenzyme A synthetase ACSM4, mitochondrialChromosome-12Acyl-coenzyme A synthetase ACSM4, mitochondrial
Q9C0K3ACTR3CActin-related protein 3CChromosome-7Actin-related protein 3C
O43506ADAM20Disintegrin and metalloproteinase domain-containing protein 20Chromosome-14Disintegrin and metalloproteinase domain-containing protein 20
Q9UKJ8ADAM21Disintegrin and metalloproteinase domain-containing protein 21Chromosome-14Disintegrin and metalloproteinase domain-containing protein 21
Q8TE56ADAMTS17A disintegrin and metalloproteinase with thrombospondin motifs 17Chromosome-15A disintegrin and metalloproteinase with thrombospondin motifs 17
Q8TE59ADAMTS19A disintegrin and metalloproteinase with thrombospondin motifs 19Chromosome-5A disintegrin and metalloproteinase with thrombospondin motifs 19
P59510ADAMTS20A disintegrin and metalloproteinase with thrombospondin motifs 20Chromosome-12A disintegrin and metalloproteinase with thrombospondin motifs 20
Q9UKP5ADAMTS6A disintegrin and metalloproteinase with thrombospondin motifs 6Chromosome-5A disintegrin and metalloproteinase with thrombospondin motifs 6

Related Publications

Publications to be cited for using MPP data and services

Islam, M.T. et al. Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the “Missing” Human Proteome. Journal of Proteome Research 13 (1), 76-83, doi: 10.1021/pr400794x (2014)
Islam, M.T. et al. A systematic bioinformatics approach to identify high quality MS data and functionally annotate proteins and proteomes. Methods Mol. Biol.1549, 163–176, doi: 10.1007/978-1-4939-6740-7_13 (2016)
Baker, M. S. et al. Accelerating the search for the missing proteins in the human proteome. Nat. Commun. 8, 14271 doi: 10.1038/ncomms14271 (2017).
Islam, M.T. et al. Missing ProteinPedia - under preparation.


Professor Mark S. Baker

  •  Department of Biomedical Sciences,

           Faculty of Medicine and Health Sciences,

           Level 1, 75 Talavera Rd, Macquarie University, NSW 2109, Australia

Bioinformatics, Database and Web Administration

Professor Shoba Ranganathan

  •  Department of Biomedical Sciences,

           Department of Chemistry and Biomolecular Science,

           Building F7B Room 121, Macquarie University, NSW 2109, Australia

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