A collaborative framework for human missing protein data sharing…
image source:http://filthy-frank.wikia.com/wiki/Chromosomes?file=Chromosome.jpg
brief information
The MissingProteinPedia is a protein data and information sharing web system that aims to collate any relevant data ‘Missing proteins’ as defined by neXtProt. At its core is a schema-less database-driven web system allowing captures of all PE2-4 protein PubMed data, based on gene and protein including synonyms. The database also allows unpublished, preliminary or proprietary data (e.g., antibody, MS, cell biological and genetic studies) to be shared with collaborators via a protected interface.
MissingProteinPedia facilitates the Human Proteome Project (HPP) cross-disciplinary collaboration by providing a complimentary, unfiltered, lower stringency perspective to both the HPP metrics and guidelines approaches, enabling community evaluation and scrutiny. MissingProteinPedia incorporates text mining technology to fetch and search accumulated UniProt, GeneCards, GeneRifs, PubMed PE2-4 data. Besides, MissingProteinPedia summarizes publicly available MS data from PRIDE, GPMDB, ProteomicsDB and MaxQB for relevant PE2-4 proteins. It allows community administrators to curate information before web publication.
We encourage all visitors to browse and contribute to 'finding' these proteins by sharing any relevant information on them that we may have missed!
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list of proteins
| Protein ID | Gene ID | Protein Name | Chromosome ID | Gene Name | Tag(s) | |
|---|---|---|---|---|---|---|
| Q96L03 | SPATA17 | Spermatogenesis-associated protein 17 | Chromosome-1 | Spermatogenesis-associated protein 17 | ||
| Q5JQS5 | OR2B11 | Olfactory receptor 2B11 | Chromosome-1 | Olfactory receptor 2B11 | ||
| Q3BBV0 | NBPF1 | Neuroblastoma breakpoint family member 1 | Chromosome-1 | Neuroblastoma breakpoint family member 1 | ||
| Q6IF00 | OR2T2 | Olfactory receptor 2T2 | Chromosome-1 | Olfactory receptor 2T2 | ||
| Q5T197 | DCST1 | DC-STAMP domain-containing protein 1 | Chromosome-1 | DC-STAMP domain-containing protein 1 | ||
| Q02575 | NHLH1 | Helix-loop-helix protein 1 | Chromosome-1 | Helix-loop-helix protein 1 | ||
| Q68G75 | LEMD1 | LEM domain-containing protein 1 | Chromosome-1 | LEM domain-containing protein 1 | ||
| Q9Y543 | HES2 | Transcription factor HES-2 | Chromosome-1 | Transcription factor HES-2 | ||
| Q8TDD5 | MCOLN3 | Mucolipin-3 | Chromosome-1 | Mucolipin-3 | ||
| Q32ZL2 | LPPR5 | Lipid phosphate phosphatase-related protein type 5 | Chromosome-1 | Lipid phosphate phosphatase-related protein type 5 | ||
| P0DMP2 | SRGAP2B | SLIT-ROBO Rho GTPase-activating protein 2B | Chromosome-1 | SLIT-ROBO Rho GTPase-activating protein 2B | ||
| Q96PI1 | SPRR4 | Small proline-rich protein 4 | Chromosome-1 | Small proline-rich protein 4 | ||
| Q9BZJ8 | GPR61 | Probable G-protein coupled receptor 61 | Chromosome-1 | Probable G-protein coupled receptor 61 | ||
| Q96DD0 | LRRC39 | Leucine-rich repeat-containing protein 39 | Chromosome-1 | Leucine-rich repeat-containing protein 39 | ||
| Q6PXP3 | SLC2A7 | Solute carrier family 2, facilitated glucose transporter member 7 | Chromosome-1 | Solute carrier family 2, facilitated glucose transporter member 7 | ||
| Q5XKL5 | BTBD8 | BTB/POZ domain-containing protein 8 | Chromosome-1 | BTB/POZ domain-containing protein 8 | ||
| P22532 | SPRR2D | Small proline-rich protein 2D | Chromosome-1 | Small proline-rich protein 2D | ||
| Q9HCC6 | HES4 | Transcription factor HES-4 | Chromosome-1 | Transcription factor HES-4 | ||
| Q96JT2 | SLC45A3 | Solute carrier family 45 member 3 | Chromosome-1 | Solute carrier family 45 member 3 | ||
| Q9Y5M6 | OCLM | Oculomedin | Chromosome-1 | Oculomedin |
Publications to be cited for using MPP data and services
| Islam, M.T. et al. Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the “Missing” Human Proteome. Journal of Proteome Research 13 (1), 76-83, doi: 10.1021/pr400794x (2014) |
| Islam, M.T. et al. A systematic bioinformatics approach to identify high quality MS data and functionally annotate proteins and proteomes. Methods Mol. Biol.1549, 163–176, doi: 10.1007/978-1-4939-6740-7_13 (2016) |
| Baker, M. S. et al. Accelerating the search for the missing proteins in the human proteome. Nat. Commun. 8, 14271 doi: 10.1038/ncomms14271 (2017). |
| Islam, M.T. et al. Missing ProteinPedia - under preparation. |
All to contact us
Professor Mark S. Baker
Professor Shoba Ranganathan