A collaborative framework for human missing protein data sharing…
image source:http://filthy-frank.wikia.com/wiki/Chromosomes?file=Chromosome.jpg
brief information
The MissingProteinPedia is a protein data and information sharing web system that aims to collate any relevant data ‘Missing proteins’ as defined by neXtProt. At its core is a schema-less database-driven web system allowing captures of all PE2-4 protein PubMed data, based on gene and protein including synonyms. The database also allows unpublished, preliminary or proprietary data (e.g., antibody, MS, cell biological and genetic studies) to be shared with collaborators via a protected interface.
MissingProteinPedia facilitates the Human Proteome Project (HPP) cross-disciplinary collaboration by providing a complimentary, unfiltered, lower stringency perspective to both the HPP metrics and guidelines approaches, enabling community evaluation and scrutiny. MissingProteinPedia incorporates text mining technology to fetch and search accumulated UniProt, GeneCards, GeneRifs, PubMed PE2-4 data. Besides, MissingProteinPedia summarizes publicly available MS data from PRIDE, GPMDB, ProteomicsDB and MaxQB for relevant PE2-4 proteins. It allows community administrators to curate information before web publication.
We encourage all visitors to browse and contribute to 'finding' these proteins by sharing any relevant information on them that we may have missed!
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list of proteins
| Protein ID | Gene ID | Protein Name | Chromosome ID | Gene Name | Tag(s) | |
|---|---|---|---|---|---|---|
| Q9Y2H8 | ZNF510 | Zinc finger protein 510 | Chromosome-9 | Zinc finger protein 510 | ||
| Q7Z4J2 | GLT6D1 | Glycosyltransferase 6 domain-containing protein 1 | Chromosome-9 | Glycosyltransferase 6 domain-containing protein 1 | ||
| P83859 | QRFP | Orexigenic neuropeptide QRFP | Chromosome-9 | Orexigenic neuropeptide QRFP | ||
| Q86WN2 | IFNE | Interferon epsilon | Chromosome-9 | Interferon epsilon | ||
| Q8NGR6 | OR1B1 | Olfactory receptor 1B1 | Chromosome-9 | Olfactory receptor 1B1 | ||
| A6NGG3 | C9orf92 | Putative uncharacterized protein C9orf92 | Chromosome-9 | Putative uncharacterized protein C9orf92 | ||
| Q5SZB4 | C9orf50 | Uncharacterized protein C9orf50 | Chromosome-9 | Uncharacterized protein C9orf50 | ||
| Q8WX39 | LCN9 | Epididymal-specific lipocalin-9 | Chromosome-9 | Epididymal-specific lipocalin-9 | ||
| A6NKF2 | ARID3C | AT-rich interactive domain-containing protein 3C | Chromosome-9 | AT-rich interactive domain-containing protein 3C | ||
| Q6ZUB1 | SPATA31E1 | Spermatogenesis-associated protein 31E1 | Chromosome-9 | Spermatogenesis-associated protein 31E1 | ||
| Q8NGS5 | OR13C4 | Olfactory receptor 13C4 | Chromosome-9 | Olfactory receptor 13C4 | ||
| Q8NGS7 | OR13C8 | Olfactory receptor 13C8 | Chromosome-9 | Olfactory receptor 13C8 | ||
| Q8WXT5 | FOXD4L4 | Forkhead box protein D4-like 4 | Chromosome-9 | Forkhead box protein D4-like 4 | ||
| Q9Y5R5 | DMRT2 | Doublesex- and mab-3-related transcription factor 2 | Chromosome-9 | Doublesex- and mab-3-related transcription factor 2 | ||
| Q68D42 | TMEM215 | Transmembrane protein 215 | Chromosome-9 | Transmembrane protein 215 | ||
| Q99811 | PRRX2 | Paired mesoderm homeobox protein 2 | Chromosome-9 | Paired mesoderm homeobox protein 2 | ||
| Q9Y581 | INSL6 | Insulin-like peptide INSL6 | Chromosome-9 | Insulin-like peptide INSL6 | ||
| Q9P2X7 | DEC1 | Deleted in esophageal cancer 1 | Chromosome-9 | Deleted in esophageal cancer 1 | ||
| P05015 | IFNA16 | Interferon alpha-16 | Chromosome-9 | Interferon alpha-16 | ||
| Q7Z6K4 | NRARP | Notch-regulated ankyrin repeat-containing protein | Chromosome-9 | Notch-regulated ankyrin repeat-containing protein |
Publications to be cited for using MPP data and services
| Islam, M.T. et al. Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the “Missing” Human Proteome. Journal of Proteome Research 13 (1), 76-83, doi: 10.1021/pr400794x (2014) |
| Islam, M.T. et al. A systematic bioinformatics approach to identify high quality MS data and functionally annotate proteins and proteomes. Methods Mol. Biol.1549, 163–176, doi: 10.1007/978-1-4939-6740-7_13 (2016) |
| Baker, M. S. et al. Accelerating the search for the missing proteins in the human proteome. Nat. Commun. 8, 14271 doi: 10.1038/ncomms14271 (2017). |
| Islam, M.T. et al. Missing ProteinPedia - under preparation. |
All to contact us
Professor Mark S. Baker
Professor Shoba Ranganathan