LCN12:Epididymal-specific lipocalin-12

Gene Name
Epididymal-specific lipocalin-12
Protein ID
Q6JVE5
Chromosome ID
9
HPP Status
2
Protein Name
Epididymal-specific lipocalin-12
Synonyms

epididymal-specific lipocalin-12

lipocalin 12

lipocalcin 12


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=LCN12 ]
Chromosomal Position
9q34.3 | Start:136949551 End:136949551
Sequence
Q6JVE5.fasta
Description

Entrez Gene Summary for LCN12
Members of the lipocalin family, such as LCN12, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 (PubMed 15363845)).(supplied by OMIM, Aug 2009)

UniProtKB Summary for LCN12
Function: Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility (By similarity)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=LCN12 ]
External IDs
Hgnc ID: 28733 EntrezGene ID: 286256 Ensembl ID: ENSG00000184925
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=LCN12 ]
Reference Source
http://www.nextprot.org

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalian with experimental evidenceLCN12_HUMANLCN12_RAT19216353.3784.975131192311932E-50194
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
LCN12_HUMANIPR002972GO:0005215FamilyProstaglandin D synthaseMolecular Functiontransporter activity
LCN12_HUMANIPR002972GO:0006629FamilyProstaglandin D synthaseBiological Processlipid metabolic process
LCN12_HUMANIPR002972GO:0006810FamilyProstaglandin D synthaseBiological Processtransport
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




Showing 1-1 of 1 item.

PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
RHTSRLAVLR0.0209951897637487,Mascot:expectation;22.72,Mascot:score;PXD000039_27368_21816_Q6JVE5_RHTSRLAVLRPXD000039;PRIDE_Exp_Complete_Ac_27368.xml;spectrum=21816
Evidence File
/mnt/mpp/ms_data/Q6JVE5_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive