BSX:Brain-specific homeobox protein homolog

Gene Name
Brain-specific homeobox protein homolog
Protein ID
Q3C1V8
Chromosome ID
11
HPP Status
2
Protein Name
Brain-specific homeobox protein homolog
Synonyms

brain-specific homeobox protein homolog

BSX1

brain-specific homeobox

brain specific homeobox


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=BSX ]
Chromosomal Position
11q24.1 | Start:122977570 End:122977570
Sequence
Q3C1V8.fasta
Description

UniProtKB Summary for BSX
Function: DNA binding protein that function as transcriptional activator. Is essentiel for normal postnatal growth and nursing. Is an essential factor for neuronal neuropeptide Y and agouti-related peptide function and locomotory behavior in the control of energy balance (By similarity)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=BSX ]
External IDs
Hgnc ID: 20450 EntrezGene ID: 390259 Ensembl ID: ENSG00000188909
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=BSX ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
18855024Data suggest that BSX is essential for global cognitive function and that haplo-insufficiency may cause severe mental retardation, and that deletion of Neurogranin2010-01-21
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalian with experimental evidenceBSH_HUMANBSH_MOUSE23323395.7110091123312323.00E-110393
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
BSH_HUMANIPR001356GO:0003700DomainHomeobox domainMolecular Functionsequence-specific DNA binding transcription factor activity
BSH_HUMANIPR001356GO:0043565DomainHomeobox domainMolecular Functionsequence-specific DNA binding
BSH_HUMANIPR009057GO:0003677DomainHomeodomain-likeMolecular FunctionDNA binding
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
No results found.
Evidence File
/mnt/mpp/ms_data/Q3C1V8_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q3C1V8_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB