IFNA16:Interferon alpha-16

Gene Name
Interferon alpha-16
Protein ID
P05015
Chromosome ID
9
HPP Status
2
Protein Name
Interferon alpha-16
Synonyms

interferon alpha-WA

IFN-alphaO

IFN-alpha-N-protein

IFN-alpha-16

Interferon alpha-WA

interferon, alpha 16

interferon alpha-16


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=IFNA16 ]
Chromosomal Position
9p21.3 | Start:21216373 End:21216373
Sequence
P05015.fasta
Description

UniProtKB Summary for IFNA16
Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=IFNA16 ]
External IDs
Hgnc ID: 5421 EntrezGene ID: 3449 Ensembl ID: ENSG00000147885
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=IFNA16 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
20574843Observational study of gene-disease association. (HuGE Navigator)2010-09-15
20588308Observational study of gene-disease association. (HuGE Navigator)2010-09-15
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalian with experimental evidenceIFN16_HUMANIFNA5_MOUSE18918960.85100740118911894E-64239
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
IFN16_HUMANIPR000471GO:0005126FamilyInterferon alpha/beta/deltaMolecular Functioncytokine receptor binding
IFN16_HUMANIPR000471GO:0005576FamilyInterferon alpha/beta/deltaCellular Componentextracellular region
IFN16_HUMANIPR000471GO:0006952FamilyInterferon alpha/beta/deltaBiological Processdefense response
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

KEGG Pathways

Pathway IDDatabase NamePathway Name
hsa04060KEGG PATHWAYCytokine-cytokine receptor interaction
hsa04140KEGG PATHWAYRegulation of autophagy
hsa04620KEGG PATHWAYToll-like receptor signaling pathway
hsa04622KEGG PATHWAYRIG-I-like receptor signaling pathway
hsa04623KEGG PATHWAYCytosolic DNA-sensing pathway
hsa04630KEGG PATHWAYJak-STAT signaling pathway
hsa04650KEGG PATHWAYNatural killer cell mediated cytotoxicity
hsa05152KEGG PATHWAYTuberculosis
hsa05160KEGG PATHWAYHepatitis C
hsa05162KEGG PATHWAYMeasles
hsa05164KEGG PATHWAYInfluenza A
hsa05168KEGG PATHWAYHerpes simplex infection
hsa05320KEGG PATHWAYAutoimmune thyroid disease
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/P05015_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
No results found.
Evidence File
/mnt/mpp/ms_data/P05015_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Proteomics DB

Evidence File
/mnt/mpp/ms_data/P05015_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB