INSL6:Insulin-like peptide INSL6

Gene Name
Insulin-like peptide INSL6
Protein ID
Q9Y581
Chromosome ID
9
HPP Status
1
Protein Name
Insulin-like peptide INSL6
Synonyms

insulin-like peptide 5

"relaxin/insulin-like factor 1"

RIF1

Relaxin/insulin-like factor 1

insulin-like 6

insulin-like peptide INSL6

Insulin-like peptide 6

insulin-like peptide 6

relaxin/insulin-like factor 1


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=INSL6 ]
Chromosomal Position
9p24.1 | Start:5131979 End:5131979
Sequence
Q9Y581.fasta
Description

Entrez Gene Summary for INSL6
The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. This gene is preferentially expressed in testis. Its expression in testis is restricted to interstitial cells surrounding seminiferous tubules, which suggests a role in sperm development and fertilization. (provided by RefSeq, Jul 2008)

UniProtKB Summary for INSL6
Function: May have a role in sperm development and fertilization

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=INSL6 ]
External IDs
Hgnc ID: 6089 EntrezGene ID: 11172 Ensembl ID: ENSG00000120210
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=INSL6 ]
Reference Source
http://www.nextprot.org

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalianINSL6_HUMANINSL6_BOVIN21319063.6889.262417202142002E-60229
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
INSL6_HUMANIPR016179GO:0005179DomainInsulin-likeMolecular Functionhormone activity
INSL6_HUMANIPR016179GO:0005576DomainInsulin-likeCellular Componentextracellular region
INSL6_HUMANIPR017100GO:0005179FamilyInsulin-like peptide 6Molecular Functionhormone activity
INSL6_HUMANIPR017100GO:0005576FamilyInsulin-like peptide 6Cellular Componentextracellular region
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
No results found.
Evidence File
/mnt/mpp/ms_data/Q9Y581_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Showing 1-1 of 1 item.

Proteomics DB

Peptide SequenceSearch EngineScoreThreshold ScoreIdentification IDExperiment IDAnnotation
EELSIACLPYIDFKMaxquant131.170551913050-1
Evidence File
/mnt/mpp/ms_data/Q9Y581_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB