GLT6D1:Glycosyltransferase 6 domain-containing protein 1

Gene Name
Glycosyltransferase 6 domain-containing protein 1
Protein ID
Q7Z4J2
Chromosome ID
9
HPP Status
2
Protein Name
Glycosyltransferase 6 domain-containing protein 1
Synonyms

GT6M7

galactosyltransferase family 6 domain-containing 1

GLTDC1

galactosyltransferase family 6 domain containing 1

Galactosyltransferase family 6 domain-containing 1

glycosyltransferase 6 domain containing 1

glycosyltransferase 6 domain-containing protein 1

EC 2.4.1.-


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=GLT6D1 ]
Chromosomal Position
9q34.3 | Start:135623656 End:135623656
Sequence
Q7Z4J2.fasta
Description

Entrez Gene Summary for GLT6D1
The GT6 glycosyltransferases gene family, which includes the ABO blood group (ABO; MIM 110300) and GLT6D1, shows a complex evolution pattern, with multiple events of gain and loss in different mammal species. In humans, the ABO gene is considered the sole functional member, although the O allele is null and is fixed in certain populations (summary by Casals et al. (2009) (PubMed 19218399)).(supplied by OMIM, Jan 2011)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=GLT6D1 ]
External IDs
Hgnc ID: 23671 EntrezGene ID: 360203 Ensembl ID: ENSG00000204007
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=GLT6D1 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
19897590GLT6D1 is a susceptibility locus for periodontitis.2010-03-29
19897590Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)2009-12-02
20800603Observational study of gene-disease association. (HuGE Navigator)2010-12-05
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalian with experimental evidenceGL6D1_HUMANGGTA1_BOVIN30828953.9893.83131120306723601E-89325
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
GL6D1_HUMANIPR005076GO:0005975FamilyGlycosyl transferase, family 6Biological Processcarbohydrate metabolic process
GL6D1_HUMANIPR005076GO:0016020FamilyGlycosyl transferase, family 6Cellular Componentmembrane
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/Q7Z4J2_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
No results found.
Evidence File
/mnt/mpp/ms_data/Q7Z4J2_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q7Z4J2_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB