NPAS1:Neuronal PAS domain-containing protein 1

Gene Name
Neuronal PAS domain-containing protein 1
Protein ID
Q99742
Chromosome ID
19
HPP Status
2
Protein Name
Neuronal PAS domain-containing protein 1
Synonyms

PASD5

neuronal PAS domain-containing protein 1

basic-helix-loop-helix-PAS protein MOP5

bHLHe11

member of PAS protein 5

Basic-helix-loop-helix-PAS protein MOP5

Class E basic helix-loop-helix protein 11

Neuronal PAS1

neuronal PAS1

"neuronal PAS1"

BHLHE11

neuronal PAS domain protein 1

MOP5

Member of PAS protein 5

class E basic helix-loop-helix protein 11

PAS domain-containing protein 5

member of PAS superfamily 5

"member of PAS superfamily 5"


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=NPAS1 ]
Chromosomal Position
19q13.32 | Start:47019820 End:47019820
Sequence
Q99742.fasta
Description

Entrez Gene Summary for NPAS1
The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development. (provided by RefSeq, Jul 2008)

UniProtKB Summary for NPAS1
Function: May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level (By similarity)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=NPAS1 ]
External IDs
Hgnc ID: 7894 EntrezGene ID: 4861 Ensembl ID: ENSG00000130751
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=NPAS1 ]
Reference Source
http://www.nextprot.org

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalian with experimental evidenceNPAS1_HUMANNPAS1_MOUSE59059485.69100.68812159015940.00E+00780
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




Showing 1-12 of 12 items.

gpmDB

Peptide SequenceEvidence LevelLog ENumber Of ObservationSpectraAccession IDProteotypicityAnnotation
GSEDSGDEDPSSHPATPRPEFTSVIRgreen-9.2751ENSP00000405290Proteotypic
GSEDSGDEDPSSHPATPRPEFTSVIRgreen-9.2751ENSP00000405290Proteotypic
GSEDSGDEDPSSHPATPRPEFTSVIRgreen-9.2751ENSP00000405290Proteotypic
GSEDSGDEDPSSHPATPRPEFTSVIRgreen-9.2751ENSP00000405290Proteotypic
GSEDSGDEDPSSHPATPRPEFTSVIRgreen-7.8751ENSP00000405290Proteotypic
GSEDSGDEDPSSHPATPRPEFTSVIRgreen-7.8751ENSP00000405290Proteotypic
GSEDSGDEDPSSHPATPRPEFTSVIRgreen-7.8751ENSP00000405290Proteotypic
GSEDSGDEDPSSHPATPRPEFTSVIRgreen-7.8751ENSP00000405290Proteotypic
GSEDSGDEDPSSHPATPRPEFTSVIRgreen-7.4751ENSP00000405290Proteotypic
GSEDSGDEDPSSHPATPRPEFTSVIRgreen-7.4751ENSP00000405290Proteotypic
GSEDSGDEDPSSHPATPRPEFTSVIRgreen-7.4751ENSP00000405290Proteotypic
GSEDSGDEDPSSHPATPRPEFTSVIRgreen-7.4751ENSP00000405290Proteotypic
Evidence File
/mnt/mpp/ms_data/Q99742_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


Showing 1-2 of 2 items.

PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
ASGYKVIHVTGRLR0.00686062630498313,Mascot:expectation;25.95,Mascot:score;PXD001323_39735_6715_Q99742_ASGYKVIHVTGRLRPXD001323;hmf_TGFb_cyt2_3.mgf;index=5937
ASGYKVIHVTGRLR22.28,Mascot:score;0.0159721641227378,Mascot:expectation;PXD001323_39740_5611_Q99742_ASGYKVIHVTGRLRPXD001323;hmf_TGFb_cyt2b_5.mgf;index=29565
Evidence File
/mnt/mpp/ms_data/Q99742_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Showing 1-1 of 1 item.

Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q99742_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB