OC90:Otoconin-90

Gene Name
Otoconin-90
Protein ID
Q02509
Chromosome ID
8
HPP Status
2
Protein Name
Otoconin-90
Synonyms

phospholipase A2 homolog

otoconin 90

Oc90

otoconin-90

PLA2L

Phospholipase A2 homolog


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=OC90 ]
Chromosomal Position
8q24.22 | Start:132024220 End:132024220
Sequence
Q02509.fasta
Description

UniProtKB Summary for OC90
Function: It is unlikely that this protein has phospholipase A2 activity

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=OC90 ]
External IDs
Hgnc ID: 8100 EntrezGene ID: 729330 Ensembl ID: ENSG00000253117
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=OC90 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
24748133calcium carbonate crystal growth data demonstrate that Otolin-1 and OC90 modulate in vitro calcite crystal morphology but neither protein is sufficient to produce the shape of otoconia2015-01-17
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalian with experimental evidenceOC90_HUMANOC90_MOUSE49349368.361001485149314854E-180627
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
OC90_HUMANIPR001211GO:0004623FamilyPhospholipase A2Molecular Functionphospholipase A2 activity
OC90_HUMANIPR001211GO:0005509FamilyPhospholipase A2Molecular Functioncalcium ion binding
OC90_HUMANIPR001211GO:0016042FamilyPhospholipase A2Biological Processlipid catabolic process
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/Q02509_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


Showing 1-1 of 1 item.

PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
KAGHDQEGVGAAR0.0151767927769158,Mascot:expectation;19.39,Mascot:score;PXD001326_39771_21029_Q02509_KAGHDQEGVGAARPXD001326;tumor_cyt_3b.mgf;index=51871
Evidence File
/mnt/mpp/ms_data/Q02509_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q02509_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB