OC90:Otoconin-90
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Gene Name
Otoconin-90 |
Protein ID
Q02509 |
Chromosome ID
8 |
HPP Status
2 |
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Protein Name
Otoconin-90 |
Synonyms
phospholipase A2 homolog otoconin 90 Oc90 otoconin-90 PLA2L Phospholipase A2 homolog [Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=OC90  ] |
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Chromosomal Position
8q24.22 | Start:132024220 End:132024220 |
Sequence
Q02509.fasta |
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Description
UniProtKB Summary for OC90Function: It is unlikely that this protein has phospholipase A2 activity [Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=OC90 ] |
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External IDs
Hgnc ID: 8100 EntrezGene ID: 729330 Ensembl ID: ENSG00000253117 [Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=OC90 ] |
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Reference Source
http://www.nextprot.org |
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Gene Reference Into Function (GeneRIF)
| PubMed ID | GeneRIF Text | Last Update |
|---|---|---|
| 24748133 | calcium carbonate crystal growth data demonstrate that Otolin-1 and OC90 modulate in vitro calcite crystal morphology but neither protein is sufficient to produce the shape of otoconia | 2015-01-17 |
| Reference http://www.ncbi.nlm.nih.gov/gene/about-generif ftp://ftp.ncbi.nih.gov/gene/GeneRIF/ | ||
OMICSDI Browser
Relevant citations within the PubMed literature
Putative/known Functions
Localisation
Homologues, Orthologues, Paralogues and Family
Sequence Similarity and Functional Annotation
Sequence Similarity
| Db Name | Query Uni | Subject Uni | Sequence Length | Alignment Length | Identity | Coverage | Mismatches | Gap Openings | Query Start | Query End | Subject Start | Subject End | Evalue | Bit Score |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Reviewed non-human mammalian with experimental evidence | OC90_HUMAN | OC90_MOUSE | 493 | 493 | 68.36 | 100 | 148 | 5 | 1 | 493 | 1 | 485 | 4E-180 | 627 |
| Reference Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83. | ||||||||||||||
InterProScan Annotation
| Uniprot ID | Interpro ID | Go ID | Type | Name | Category | Description |
|---|---|---|---|---|---|---|
| OC90_HUMAN | IPR001211 | GO:0004623 | Family | Phospholipase A2 | Molecular Function | phospholipase A2 activity |
| OC90_HUMAN | IPR001211 | GO:0005509 | Family | Phospholipase A2 | Molecular Function | calcium ion binding |
| OC90_HUMAN | IPR001211 | GO:0016042 | Family | Phospholipase A2 | Biological Process | lipid catabolic process |
| Reference Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83. | ||||||