LEPROTL1:Leptin receptor overlapping transcript-like 1

Gene Name
Leptin receptor overlapping transcript-like 1
Protein ID
O95214
Chromosome ID
8
HPP Status
1
Protein Name
Leptin receptor overlapping transcript-like 1
Synonyms

endospanin-2

HSPC112

leptin receptor overlapping transcript-like 1

Vps55

Endospanin-2

my047


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=LEPROTL1 ]
Chromosomal Position
8p12 | Start:30095398 End:30095398
Sequence
O95214.fasta
Description

UniProtKB Summary for LEPROTL1
Function: Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=LEPROTL1 ]
External IDs
Hgnc ID: 6555 EntrezGene ID: 23484 Ensembl ID: ENSG00000104660
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=LEPROTL1 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
19876004Observational study of gene-disease association. (HuGE Navigator)2009-12-02
19907080Transgenic mice expressing either human LEPROT or human LEPROTL1 displayed growth retardation, reduced plasma IGF1 levels, and impaired hepatic sensitivity to GH, as measured by STAT5 phosphorylation and Socs2 mRNA expression.2010-01-21
20734064Observational study of gene-disease association. (HuGE Navigator)2010-12-05
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation



Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




Showing 1-20 of 1,776 items.

gpmDB

Peptide SequenceEvidence LevelLog ENumber Of ObservationSpectraAccession IDProteotypicityAnnotation
LVDDTDAMSNACKgreen-15.050491ENSP00000314625Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000314625Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000314625Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000314625Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000314625Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000314625Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000314625Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000314625Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000412803Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000412803Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000412803Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000412803Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000412803Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000412803Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000412803Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000412803Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000314625Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000314625Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000314625Proteotypic
LVDDTDAMSNACKgreen-15.050491ENSP00000314625Proteotypic
Evidence File
/mnt/mpp/ms_data/O95214_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


Showing 1-1 of 1 item.

MaxQB

Peptide SequenceSearch EngineBest ScoreBest Evidence IDBest Raw File IDBest Msms ScanAnnotation
IVDDTDAMSNACKMaxQuant150.49131137020120508_EXQ4_NaNa_SA_12cellines_cellline0524315
Evidence File
/mnt/mpp/ms_data/O95214_maxqb.txt
Reference
Christoph Schaab, Tamar Geiger, Gabriele Stoehr, Juergen Cox and Matthias Mann: "Analysis of high-accuracy, quantitative proteomics data in the MaxQB database", Mol Cell Proteomics 11 (2012) M111.014068.
http://maxqb.biochem.mpg.de/mxdb/ ">MaxQB


Showing 1-20 of 120 items.

PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
LVDDTDAMSNACK1.1415999468262E-10,Mascot:expectation;104.61,Mascot:score;PXD001694_43451_53077_O95214_LVDDTDAMSNACKPXD001694;JNU 2014042697h_MGFPeaklist.mgf;index=181779
LVDDTDAMSNACK100.06,Mascot:score;3.254722302583E-10,Mascot:expectation;PXD001694_43449_11634_O95214_LVDDTDAMSNACKPXD001694;DataSETH1299_MGFPeaklist.mgf;index=12003
LVDDTDAMSNACK100.06,Mascot:score;3.254722302583E-10,Mascot:expectation;PXD001694_43449_11634_O95214_LVDDTDAMSNACKPXD001694;DataSETH1299_MGFPeaklist.mgf;index=12003
LVDDTDAMSNACK2.00855330044985E-9,Mascot:expectation;92.09,Mascot:score;PXD001694_43449_11633_O95214_LVDDTDAMSNACKPXD001694;DataSETH1299_MGFPeaklist.mgf;index=40201
LVDDTDAMSNACK2.00855330044985E-9,Mascot:expectation;92.09,Mascot:score;PXD001694_43449_11633_O95214_LVDDTDAMSNACKPXD001694;DataSETH1299_MGFPeaklist.mgf;index=40201
LVDDTDAMSNACK7.63964897806622E-9,Mascot:expectation;90.05,Mascot:score;PXD002798_56876_231_O95214_LVDDTDAMSNACKPXD002798;Day42controlmerged.mgf;index=80930
LVDDTDAMSNACK7.63964897806622E-9,Mascot:expectation;90.05,Mascot:score;PXD002798_56876_231_O95214_LVDDTDAMSNACKPXD002798;Day42controlmerged.mgf;index=80930
LVDDTDAMSNACK9.91282192044495E-9,Mascot:expectation;92.5,Mascot:score;PXD002798_56871_1292_O95214_LVDDTDAMSNACKPXD002798;Day21controlmerged.mgf;index=80919
LVDDTDAMSNACK9.91282192044495E-9,Mascot:expectation;92.5,Mascot:score;PXD002798_56871_1292_O95214_LVDDTDAMSNACKPXD002798;Day21controlmerged.mgf;index=80919
LVDDTDAMSNACK1.41624146088706E-8,Mascot:expectation;92.18,Mascot:score;PXD002798_56876_232_O95214_LVDDTDAMSNACKPXD002798;Day42controlmerged.mgf;index=80911
LVDDTDAMSNACK1.41624146088706E-8,Mascot:expectation;92.18,Mascot:score;PXD002798_56876_232_O95214_LVDDTDAMSNACKPXD002798;Day42controlmerged.mgf;index=80911
LVDDTDAMSNACK88.8,Mascot:score;1.59093451670464E-8,Mascot:expectation;PXD002798_56873_101_O95214_LVDDTDAMSNACKPXD002798;Day2controlmerged.mgf;index=80972
LVDDTDAMSNACK88.8,Mascot:score;1.59093451670464E-8,Mascot:expectation;PXD002798_56873_101_O95214_LVDDTDAMSNACKPXD002798;Day2controlmerged.mgf;index=80972
LVDDTDAMSNACK90.23,Mascot:score;3.29333875127781E-8,Mascot:expectation;PXD002798_56873_102_O95214_LVDDTDAMSNACKPXD002798;Day2controlmerged.mgf;index=80966
LVDDTDAMSNACK90.23,Mascot:score;3.29333875127781E-8,Mascot:expectation;PXD002798_56873_102_O95214_LVDDTDAMSNACKPXD002798;Day2controlmerged.mgf;index=80966
LVDDTDAMSNACK78.09,Mascot:score;5.7438319368449E-8,Mascot:expectation;PXD001694_43453_56406_O95214_LVDDTDAMSNACKPXD001694;JNU 20140426 M3_MGFPeaklist.mgf;index=200372
LVDDTDAMSNACK78.09,Mascot:score;5.7438319368449E-8,Mascot:expectation;PXD001694_43453_56406_O95214_LVDDTDAMSNACKPXD001694;JNU 20140426 M3_MGFPeaklist.mgf;index=200372
LVDDTDAMSNACK9.58864641914972E-8,Mascot:expectation;74.85,Mascot:score;PXD001694_43453_56407_O95214_LVDDTDAMSNACKPXD001694;JNU 20140426 M3_MGFPeaklist.mgf;index=2871
LVDDTDAMSNACK9.58864641914972E-8,Mascot:expectation;74.85,Mascot:score;PXD001694_43453_56407_O95214_LVDDTDAMSNACKPXD001694;JNU 20140426 M3_MGFPeaklist.mgf;index=2871
LVDDTDAMSNACK80.12,Mascot:score;1.44939336342768E-7,Mascot:expectation;PXD000449_31116_7201_O95214_LVDDTDAMSNACKPXD000449;PRIDE_Exp_Complete_Ac_31116.xml;spectrum=7201
Evidence File
/mnt/mpp/ms_data/O95214_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Showing 1-13 of 13 items.

Proteomics DB

Peptide SequenceSearch EngineScoreThreshold ScoreIdentification IDExperiment IDAnnotation
RLVDDTDAMSNACKMaxquant258.91012310068903000
LVDDTDAMSNACKMaxquant211.3807812256432320
LVDDTDAMSNACKMaxquant196.1107906330512297
LVDDTDAMSNACKMaxquant193.2807908076112296
LVDDTDAMSNACKMaxquant178.670246253726271
LVDDTDAMSNACKMaxquant169.7907908076152296
RLVDDTDAMSNACKMaxquant161.760723261782254
LVDDTDAMSNACKMaxquant143.970723093397254
LVDDTDAMSNACKMaxquant135.02012198135422993
LVDDTDAMSNACKMascot118.22470811119122
LVDDTDAMSNACKMascot121.7725670956138271
LVDDTDAMSNACKMascot99.942211944968622993
LVDDTDAMSNACKMaxquant120.87057287371-1
Evidence File
/mnt/mpp/ms_data/O95214_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB