GOT1L1:Putative aspartate aminotransferase, cytoplasmic 2

Gene Name
Putative aspartate aminotransferase, cytoplasmic 2
Protein ID
Q8NHS2
Chromosome ID
8
HPP Status
1
Protein Name
Putative aspartate aminotransferase, cytoplasmic 2
Synonyms

glutamic-oxaloacetic transaminase 1-like 1

putative aspartate aminotransferase, cytoplasmic 2

transaminase A-like protein 1

Transaminase A-like protein 1

Glutamate oxaloacetate transaminase 1-like protein 1

glutamate oxaloacetate transaminase 1-like protein 1

EC 2.6.1.-


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=GOT1L1 ]
Chromosomal Position
8p11.23 | Start:37934281 End:37934281
Sequence
Q8NHS2.fasta
Description

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=GOT1L1 ]
External IDs
Hgnc ID: 28487 EntrezGene ID: 137362 Ensembl ID: ENSG00000169154
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=GOT1L1 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
17494625Neither human hexokinase-1 nor human inorganic pyrophosphatase expression segregated concordantly with human cytoplasmic glutamic-oxaloacetic transaminase expression.2010-01-21
22360420A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.2012-04-26
25646960The rat and human homologs of mouse GOT1L1 are not involved in D-aspartate biosynthesis.2016-01-16
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
AATC2_HUMANIPR000796GO:0006520FamilyAspartate/other aminotransferaseBiological Processcellular amino acid metabolic process
AATC2_HUMANIPR000796GO:0008483FamilyAspartate/other aminotransferaseMolecular Functiontransaminase activity
AATC2_HUMANIPR004839GO:0009058DomainAminotransferase, class I/classIIBiological Processbiosynthetic process
AATC2_HUMANIPR004839GO:0030170DomainAminotransferase, class I/classIIMolecular Functionpyridoxal phosphate binding
AATC2_HUMANIPR015422GO:0003824DomainPyridoxal phosphate-dependent transferase, major region, subdomain 2Molecular Functioncatalytic activity
AATC2_HUMANIPR015422GO:0030170DomainPyridoxal phosphate-dependent transferase, major region, subdomain 2Molecular Functionpyridoxal phosphate binding
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




Showing 1-2 of 2 items.

gpmDB

Peptide SequenceEvidence LevelLog ENumber Of ObservationSpectraAccession IDProteotypicityAnnotation
HSQAIVENRVGGVHTVGDSGAFQLGVQFLRred-10.821ENSP00000303077Proteotypic
HSQAIVENRVGGVHTVGDSGAFQLGVQFLRred-10.821ENSP00000303077Proteotypic
Evidence File
/mnt/mpp/ms_data/Q8NHS2_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
No results found.
Evidence File
/mnt/mpp/ms_data/Q8NHS2_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q8NHS2_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB