AQP12A:Aquaporin-12A

Gene Name
Aquaporin-12A
Protein ID
Q8IXF9
Chromosome ID
2
HPP Status
2
Protein Name
Aquaporin-12A
Synonyms

AQP-12

AQP12

aquaporin 12

aquaporin-12A

aquaporin X2

AQPX2

aquaporin 12A


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=AQP12A ]
Chromosomal Position
2q37.3 | Start:240691845 End:240691845
Sequence
Q8IXF9.fasta
Description

UniProtKB Summary for AQP12A
Function: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=AQP12A ]
External IDs
Hgnc ID: 19941 EntrezGene ID: 375318 Ensembl ID: ENSG00000184945
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=AQP12A ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
15809071a role of AQP12 in digestive enzyme secretion such as maturation and exocytosis of secretory granules2010-01-21
23359558Built accurate 3D-models for AQP11 and AQP12 and comprehensively compared their sequence and structure to other known aquaporins.2013-08-31
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalianAQ12A_HUMANAQP12_MOUSE29528572.2896.61671127312854.00E-98355
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
AQ12A_HUMANIPR000425GO:0005215FamilyMajor intrinsic proteinMolecular Functiontransporter activity
AQ12A_HUMANIPR000425GO:0006810FamilyMajor intrinsic proteinBiological Processtransport
AQ12A_HUMANIPR000425GO:0016020FamilyMajor intrinsic proteinCellular Componentmembrane
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




Showing 1-20 of 20 items.

gpmDB

Peptide SequenceEvidence LevelLog ENumber Of ObservationSpectraAccession IDProteotypicityAnnotation
LAAQGLGMQAACTLMRgreen-13.1121ENSP00000337144Proteotypic
LAAQGLGMQAACTLMRgreen-13.1121ENSP00000337144Proteotypic
LAAQGLGMQAACTLMRgreen-13.1121ENSP00000405899Proteotypic
LAAQGLGMQAACTLMRgreen-13.1121ENSP00000405899Proteotypic
LAAQGLGMQAACTLMRgreen-13.1121ENSP00000337144Proteotypic
LAAQGLGMQAACTLMRgreen-13.1121ENSP00000337144Proteotypic
LAAQGLGMQAACTLMRgreen-13.1121ENSP00000405899Proteotypic
LAAQGLGMQAACTLMRgreen-13.1121ENSP00000405899Proteotypic
LAAQGLGMQAACTLMRgreen-10.7121ENSP00000337144Proteotypic
LAAQGLGMQAACTLMRgreen-10.7121ENSP00000337144Proteotypic
LAAQGLGMQAACTLMRgreen-10.7121ENSP00000405899Proteotypic
LAAQGLGMQAACTLMRgreen-10.7121ENSP00000405899Proteotypic
LAAQGLGMQAACTLMRgreen-10.7121ENSP00000337144Proteotypic
LAAQGLGMQAACTLMRgreen-10.7121ENSP00000337144Proteotypic
LAAQGLGMQAACTLMRgreen-10.7121ENSP00000405899Proteotypic
LAAQGLGMQAACTLMRgreen-10.7121ENSP00000405899Proteotypic
MAGLNVSLSFFFATFALCEAARRgreen-9.421ENSP00000337144Proteotypic
MAGLNVSLSFFFATFALCEAARRgreen-9.421ENSP00000405899Proteotypic
MAGLNVSLSFFFATFALCEAARRgreen-9.421ENSP00000337144Proteotypic
MAGLNVSLSFFFATFALCEAARRgreen-9.421ENSP00000405899Proteotypic
Evidence File
/mnt/mpp/ms_data/Q8IXF9_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q8IXF9_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB