MOGAT1:2-acylglycerol O-acyltransferase 1

Gene Name
2-acylglycerol O-acyltransferase 1
Protein ID
Q96PD6
Chromosome ID
2
HPP Status
2
Protein Name
2-acylglycerol O-acyltransferase 1
Synonyms

hDC2

Acyl-CoA:monoacylglycerol acyltransferase 1

diacylglycerol O-acyltransferase 2 like 1

MGAT1

DGAT2L

2-acylglycerol O-acyltransferase 1

Diacylglycerol acyltransferase 2-like protein 1

Diacylglycerol O-acyltransferase candidate 2

acyl-CoA:monoacylglycerol acyltransferase 1

diacylglycerol acyltransferase 2-like protein 1

monoacylglycerol O-acyltransferase 1

diacylglycerol O-acyltransferase candidate 2

DGAT2L1

Monoacylglycerol O-acyltransferase 1

DC2

EC 2.3.1.22


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=MOGAT1 ]
Chromosomal Position
2q36.1 | Start:222671786 End:222671786
Sequence
Q96PD6.fasta
Description

Entrez Gene Summary for MOGAT1
Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerols, the precursor of physiologically important lipids such as triacylglycerol and phospholipids (Yen et al., 2002 (PubMed 12077311)).(supplied by OMIM, Mar 2008)

UniProtKB Summary for MOGAT1
Function: Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Probably not involved in absorption of dietary fat in the small intestine (By similarity)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=MOGAT1 ]
External IDs
Hgnc ID: 18210 EntrezGene ID: 116255 Ensembl ID: ENSG00000124003
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=MOGAT1 ]
Reference Source
http://www.nextprot.org

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalian with experimental evidenceMOGT1_HUMANMOGT1_MOUSE33533572.54100920133513358E-139489
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/Q96PD6_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
No results found.
Evidence File
/mnt/mpp/ms_data/Q96PD6_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q96PD6_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB