ASB18:Ankyrin repeat and SOCS box protein 18

Gene Name
Ankyrin repeat and SOCS box protein 18
Protein ID
Q6ZVZ8
Chromosome ID
2
HPP Status
2
Protein Name
Ankyrin repeat and SOCS box protein 18
Synonyms

ankyrin repeat and SOCS box-containing 18

ankyrin repeat and SOCS box protein 18

ASB-18

ankyrin repeat and SOCS box containing 18


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=ASB18 ]
Chromosomal Position
2q37.2 | Start:236194872 End:236194872
Sequence
Q6ZVZ8.fasta
Description

UniProtKB Summary for ASB18
Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=ASB18 ]
External IDs
Hgnc ID: 19770 EntrezGene ID: 401036 Ensembl ID: ENSG00000182177
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=ASB18 ]
Reference Source
http://www.nextprot.org

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
ASB18_HUMANIPR001496GO:0035556DomainSOCS protein, C-terminalBiological Processintracellular signal transduction
ASB18_HUMANIPR002110GO:0005515RepeatAnkyrin repeatMolecular Functionprotein binding
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/Q6ZVZ8_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
No results found.
Evidence File
/mnt/mpp/ms_data/Q6ZVZ8_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Showing 1-1 of 1 item.

Proteomics DB

Peptide SequenceSearch EngineScoreThreshold ScoreIdentification IDExperiment IDAnnotation
SNSDYLPDYPLNSDLVKMascot3.7925110540813255
Evidence File
/mnt/mpp/ms_data/Q6ZVZ8_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB