NUGGC:Nuclear GTPase SLIP-GC

Gene Name
Nuclear GTPase SLIP-GC
Protein ID
Q68CJ6
Chromosome ID
8
HPP Status
2
Protein Name
Nuclear GTPase SLIP-GC
Synonyms

C8orf80

GTPase SLIP-GC

speckled-like pattern in the germinal center

nuclear GTPase, germinal center associated

Speckled-like pattern in the germinal center

"speckled-like pattern in the germinal center"

SLIP-GC

nuclear GTPase SLIP-GC

chromosome 8 open reading frame 80

EC 3.6.1.-


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=NUGGC ]
Chromosomal Position
8p21.1 | Start:28021964 End:28021964
Sequence
Q68CJ6.fasta
Description

UniProtKB Summary for NUGGC
Function: Plays a role as replication-related GTPase protein in germinal center B-cell

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=NUGGC ]
External IDs
Hgnc ID: 33550 EntrezGene ID: 389643 Ensembl ID: ENSG00000189233
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=NUGGC ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
19734146SLIP-GC is a replication-related protein in germinal center B cells whose reduction is toxic to cells through an AICDA-dependent mechanism.2010-01-21
20379614Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)2010-06-30
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
All Reviewed HumanSLIP_HUMANSLIP_HUMAN796796100100001796179601642
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
SLIP_HUMANIPR001401GO:0003924DomainDynamin, GTPase domainMolecular FunctionGTPase activity
SLIP_HUMANIPR001401GO:0005525DomainDynamin, GTPase domainMolecular FunctionGTP binding
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




Showing 1-6 of 6 items.

gpmDB

Peptide SequenceEvidence LevelLog ENumber Of ObservationSpectraAccession IDProteotypicityAnnotation
LCYEEAAQITGKred-7.4361ENSP00000345031Proteotypic
LCYEEAAQITGKred-7.4361ENSP00000345031Proteotypic
CSVIWVISDIERred-6.7201ENSP00000345031Proteotypic
CSVIWVISDIERred-6.7201ENSP00000345031Proteotypic
AGNQAIQSQRred-6.5271ENSP00000345031Proteotypic
AGNQAIQSQRred-6.5271ENSP00000345031Proteotypic
Evidence File
/mnt/mpp/ms_data/Q68CJ6_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
No results found.
Evidence File
/mnt/mpp/ms_data/Q68CJ6_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Showing 1-3 of 3 items.

Proteomics DB

Peptide SequenceSearch EngineScoreThreshold ScoreIdentification IDExperiment IDAnnotation
AEEAEELSIKMaxquant190.5606045547331
AGNQAIQSQRMaxquant130.0106046275531
AGNQAIQSQRMaxquant117.250535200850162
Evidence File
/mnt/mpp/ms_data/Q68CJ6_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB