SLCO5A1:Solute carrier organic anion transporter family member 5A1

Gene Name
Solute carrier organic anion transporter family member 5A1
Protein ID
Q9H2Y9
Chromosome ID
8
HPP Status
2
Protein Name
Solute carrier organic anion transporter family member 5A1
Synonyms

solute carrier organic anion transporter family member 5A1

solute carrier organic anion transporter family, member 5A1

OATP-RP4

OATP5A1

Solute carrier family 21 member 15

OATP-J

organic anion transporter polypeptide-related protein 4

solute carrier family 21 (organic anion transporter), member 15

OATPRP4

solute carrier family 21 member 15

SLC21A15

Organic anion transporter polypeptide-related protein 4


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=SLCO5A1 ]
Chromosomal Position
8q13.3 | Start:69667047 End:69667047
Sequence
Q9H2Y9.fasta
Description

Entrez Gene Summary for SLCO5A1
This gene encodes a 12 transmembrane domain protein that is a member of the solute carrier organic anion transporter superfamily. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Mar 2009)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=SLCO5A1 ]
External IDs
Hgnc ID: 19046 EntrezGene ID: 81796 Ensembl ID: ENSG00000137571
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=SLCO5A1 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
20379614Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)2010-06-30
20602915Haploinsufficiency of SULF1 combined with haploinsufficiency of SLCO5A1 (or the altered expression of a neighboring gene through position effect) could be necessary in the pathogenesis of MSS.2010-08-02
21278488tissue-specific localization of OATP2B1, OATP3A1 and OATP5A1 has been analyzed in normal mammary tissue and corresponding breast cancer tissues.2011-07-09
24376674SLCO5A1 is an organic anion transporting polypeptide which is involved in biological processes that require the reorganization of the cell shape, such as differentiation and migration.2014-10-11
25301452High OATP5A1 expression is associated with small cell lung cancer.2015-03-07
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
SO5A1_HUMANIPR002350GO:0005515DomainKazal domainMolecular Functionprotein binding
SO5A1_HUMANIPR004156GO:0005215FamilyOrganic anion transporter polypeptide OATPMolecular Functiontransporter activity
SO5A1_HUMANIPR004156GO:0006810FamilyOrganic anion transporter polypeptide OATPBiological Processtransport
SO5A1_HUMANIPR004156GO:0016020FamilyOrganic anion transporter polypeptide OATPCellular Componentmembrane
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/Q9H2Y9_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


Showing 1-17 of 17 items.

PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
QVITPPTVGQR0.0190809065403256,Mascot:expectation;28.08,Mascot:score;PXD000443_31020_492186_Q9H2Y9_QVITPPTVGQRPXD000443;PRIDE_Exp_Complete_Ac_31020.xml;spectrum=492186
QVITPPTVGQR0.0190809065403256,Mascot:expectation;28.08,Mascot:score;PXD000443_31020_492186_Q9H2Y9_QVITPPTVGQRPXD000443;PRIDE_Exp_Complete_Ac_31020.xml;spectrum=492186
QVITPPTVGQR28.08,Mascot:score;0.0190809065403256,Mascot:expectation;PXD000039_27365_53707_Q9H2Y9_QVITPPTVGQRPXD000039;PRIDE_Exp_Complete_Ac_27365.xml;spectrum=53707
QVITPPTVGQR28.08,Mascot:score;0.0190809065403256,Mascot:expectation;PXD000039_27365_53707_Q9H2Y9_QVITPPTVGQRPXD000039;PRIDE_Exp_Complete_Ac_27365.xml;spectrum=53707
QVITPPTVGQR28.08,Mascot:score;0.0190809065403256,Mascot:expectation;PXD000039_27365_53707_Q9H2Y9_QVITPPTVGQRPXD000039;PRIDE_Exp_Complete_Ac_27365.xml;spectrum=53707
QVITPPTVGQR25.17,Mascot:score;0.01933472521828,Mascot:expectation;PXD000443_31020_492483_Q9H2Y9_QVITPPTVGQRPXD000443;PRIDE_Exp_Complete_Ac_31020.xml;spectrum=492483
QVITPPTVGQR25.17,Mascot:score;0.01933472521828,Mascot:expectation;PXD000443_31020_492483_Q9H2Y9_QVITPPTVGQRPXD000443;PRIDE_Exp_Complete_Ac_31020.xml;spectrum=492483
QVITPPTVGQR25.17,Mascot:score;0.01933472521828,Mascot:expectation;PXD000039_27365_54004_Q9H2Y9_QVITPPTVGQRPXD000039;PRIDE_Exp_Complete_Ac_27365.xml;spectrum=54004
QVITPPTVGQR25.17,Mascot:score;0.01933472521828,Mascot:expectation;PXD000039_27365_54004_Q9H2Y9_QVITPPTVGQRPXD000039;PRIDE_Exp_Complete_Ac_27365.xml;spectrum=54004
QVITPPTVGQR25.17,Mascot:score;0.01933472521828,Mascot:expectation;PXD000039_27365_54004_Q9H2Y9_QVITPPTVGQRPXD000039;PRIDE_Exp_Complete_Ac_27365.xml;spectrum=54004
QVITPPTVGQR0.0238599651134217,Mascot:expectation;28.53,Mascot:score;PXD000039_27358_27336_Q9H2Y9_QVITPPTVGQRPXD000039;PRIDE_Exp_Complete_Ac_27358.xml;spectrum=27336
QVITPPTVGQR0.0238599651134217,Mascot:expectation;28.53,Mascot:score;PXD000039_27358_27336_Q9H2Y9_QVITPPTVGQRPXD000039;PRIDE_Exp_Complete_Ac_27358.xml;spectrum=27336
QVITPPTVGQR0.0238599651134217,Mascot:expectation;28.53,Mascot:score;PXD000039_27358_27336_Q9H2Y9_QVITPPTVGQRPXD000039;PRIDE_Exp_Complete_Ac_27358.xml;spectrum=27336
QVITPPTVGQR0.0238599651134217,Mascot:expectation;28.53,Mascot:score;PXD000039_27358_27336_Q9H2Y9_QVITPPTVGQRPXD000039;PRIDE_Exp_Complete_Ac_27358.xml;spectrum=27336
QVITPPTVGQR0.0281028589948101,Mascot:expectation;18.01,Mascot:score;PXD000039_27365_54300_Q9H2Y9_QVITPPTVGQRPXD000039;PRIDE_Exp_Complete_Ac_27365.xml;spectrum=54300
QVITPPTVGQR0.0281028589948101,Mascot:expectation;18.01,Mascot:score;PXD000039_27365_54300_Q9H2Y9_QVITPPTVGQRPXD000039;PRIDE_Exp_Complete_Ac_27365.xml;spectrum=54300
QVITPPTVGQR0.0281028589948101,Mascot:expectation;18.01,Mascot:score;PXD000039_27365_54300_Q9H2Y9_QVITPPTVGQRPXD000039;PRIDE_Exp_Complete_Ac_27365.xml;spectrum=54300
Evidence File
/mnt/mpp/ms_data/Q9H2Y9_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q9H2Y9_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB