COX7B2:Cytochrome c oxidase subunit 7B2, mitochondrial

Gene Name
Cytochrome c oxidase subunit 7B2, mitochondrial
Protein ID
Q8TF08
Chromosome ID
4
HPP Status
3
Protein Name
Cytochrome c oxidase subunit 7B2, mitochondrial
Synonyms

cytochrome c oxidase subunit 7B2, mitochondrial

cytochrome c oxidase subunit VIIb2

Cytochrome c oxidase polypeptide VIIb2

cytochrome c oxidase polypeptide VIIb2


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=COX7B2 ]
Chromosomal Position
4p12 | Start:46734827 End:46734827
Sequence
Q8TF08.fasta
Description

UniProtKB Summary for COX7B2
Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=COX7B2 ]
External IDs
Hgnc ID: 24381 EntrezGene ID: 170712 Ensembl ID: ENSG00000170516
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=COX7B2 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
15623157codon 26 of COX7B2 gene might be evolutionarily conserved and the rare variation His26Gln may be associated with a high risk of nasopharyngeal carcinoma2010-01-21
19064571Observational study of gene-disease association. (HuGE Navigator)2009-09-20
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalian with experimental evidenceCX7B2_HUMANCOX7B_BOVIN81807598.772002811801E-27116
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
CX7B2_HUMANIPR008433GO:0004129FamilyCytochrome C oxidase, subunit VIIBMolecular Functioncytochrome-c oxidase activity
CX7B2_HUMANIPR008433GO:0005746FamilyCytochrome C oxidase, subunit VIIBCellular Componentmitochondrial respiratory chain
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

KEGG Pathways

Pathway IDDatabase NamePathway Name
hsa00190KEGG PATHWAYOxidative phosphorylation
hsa01100KEGG PATHWAYMetabolic pathways
hsa04260KEGG PATHWAYCardiac muscle contraction
hsa05010KEGG PATHWAYAlzheimer's disease
hsa05012KEGG PATHWAYParkinson's disease
hsa05016KEGG PATHWAYHuntington's disease
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q8TF08_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB