TRAM1L1:Translocating chain-associated membrane protein 1-like 1

Gene Name
Translocating chain-associated membrane protein 1-like 1
Protein ID
Q8N609
Chromosome ID
4
HPP Status
2
Protein Name
Translocating chain-associated membrane protein 1-like 1
Synonyms

translocation associated membrane protein 1-like 1

translocating chain-associated membrane protein 1-like 1


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=TRAM1L1 ]
Chromosomal Position
4q26 | Start:117083554 End:117083554
Sequence
Q8N609.fasta
Description

UniProtKB Summary for TRAM1L1
Function: Stimulatory or required for the translocation of secretory proteins across the ER membrane (By similarity)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=TRAM1L1 ]
External IDs
Hgnc ID: 28371 EntrezGene ID: 133022 Ensembl ID: ENSG00000174599
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=TRAM1L1 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
20332099Observational study of gene-disease association. (HuGE Navigator)2010-06-30
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalian with experimental evidenceTR1L1_HUMANTRAM1_CANFA36937471.66101.361012136913745E-142499
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
TR1L1_HUMANIPR006634GO:0016021DomainTRAM/LAG1/CLN8 homology domainCellular Componentintegral to membrane
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




Showing 1-4 of 4 items.

gpmDB

Peptide SequenceEvidence LevelLog ENumber Of ObservationSpectraAccession IDProteotypicityAnnotation
NPDALTGNVNVLAAKred-12.141ENSP00000309402Proteotypic
NPDALTGNVNVLAAKred-12.141ENSP00000309402Proteotypic
NPDALTGNVNVLAAKred-6.741ENSP00000309402Proteotypic
NPDALTGNVNVLAAKred-6.741ENSP00000309402Proteotypic
Evidence File
/mnt/mpp/ms_data/Q8N609_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q8N609_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB