GYPE:Glycophorin-E

Gene Name
Glycophorin-E
Protein ID
P15421
Chromosome ID
4
HPP Status
2
Protein Name
Glycophorin-E
Synonyms

MNS

glycophorin-E

glycophorin E (MNS blood group)

GPE

MiIX

glycophorin E


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=GYPE ]
Chromosomal Position
4q31.21 | Start:143870867 End:143870867
Sequence
P15421.fasta
Description

Entrez Gene Summary for GYPE
The protein encoded by this gene is a sialoglycoprotein and a type I membrane protein. It is a member of a gene family with GPA and GPB genes. This encoded protein might carry the M blood group antigen. GYPA, GYPB, and GYPE are organized in tandem on chromosome 4. This gene might have derived from an ancestral gene common to the GPB gene by gene duplication. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. (provided by RefSeq, Jul 2008)

UniProtKB Summary for GYPE
Function: This protein is a minor sialoglycoprotein in human erythrocyte membranes

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=GYPE ]
External IDs
Hgnc ID: 4705 EntrezGene ID: 2996 Ensembl ID: ENSG00000197465
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=GYPE ]
Reference Source
http://www.nextprot.org

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalianGLPE_HUMANGLPB_PANTR782892.8635.9201281285.00E-0750
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
GLPE_HUMANIPR001195GO:0016021FamilyGlycophorinCellular Componentintegral to membrane
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/P15421_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM