ADAMTS19:A disintegrin and metalloproteinase with thrombospondin motifs 19

Gene Name
A disintegrin and metalloproteinase with thrombospondin motifs 19
Protein ID
Q8TE59
Chromosome ID
5
HPP Status
1
Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 19
Synonyms

ADAMTS-19

ADAM metallopeptidase with thrombospondin type 1 motif, 19

ADAM-TS19

a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 19

A disintegrin and metalloproteinase with thrombospondin motifs 19

ADAM-TS 19

EC 3.4.24.-


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=ADAMTS19 ]
Chromosomal Position
5q23.3 | Start:129460265 End:129460265
Sequence
Q8TE59.fasta
Description

Entrez Gene Summary for ADAMTS19
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member. (provided by RefSeq, Jul 2008)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=ADAMTS19 ]
External IDs
Hgnc ID: 17111 EntrezGene ID: 171019 Ensembl ID: ENSG00000145808
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=ADAMTS19 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
19508998Although limited by sample size, this proof-of-principle study's findings reveal ADAMTS19 as a possible candidate gene for premature ovarian failure and thus a larger follow-up study is warranted.2010-01-21
19508998Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)2009-12-02
24014609Synergistic interactions were detected between SNPs, including a non-synonymous SNP, and diplotypes within IGF2R and ADAMTS19 which may contribute to POF.2014-06-21
25051287We found that the AAAAA, AGGAG, and AGGGA haplotypes in ACVR2B were associated with susceptibility to Premature Ovarian Failure when they also had at least one CATAG haplotype in ADAMTS19.2016-02-27
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation



Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
No results found.
Evidence File
/mnt/mpp/ms_data/Q8TE59_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Showing 1-3 of 3 items.

Proteomics DB

Peptide SequenceSearch EngineScoreThreshold ScoreIdentification IDExperiment IDAnnotation
EAEDCEDYSKMascot69.0213343895327-1
GVGGGGSARMaxquant124.08011650722922689
EAEDCEDYSKMaxquant117.02056270195-1
Evidence File
/mnt/mpp/ms_data/Q8TE59_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB