C2CD4A:C2 calcium-dependent domain-containing protein 4A

Gene Name
C2 calcium-dependent domain-containing protein 4A
Protein ID
Q8NCU7
Chromosome ID
15
HPP Status
2
Protein Name
C2 calcium-dependent domain-containing protein 4A
Synonyms

Protein FAM148A

C2 calcium-dependent domain-containing protein 4A

nuclear localized factor 1

nuclear-localized factor 1

FAM148A

Nuclear-localized factor 1

"nuclear localized factor 1"

family with sequence similarity 148, member A

NLF1

C2 calcium-dependent domain containing 4A


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=C2CD4A ]
Chromosomal Position
15q22.2 | Start:62066977 End:62066977
Sequence
Q8NCU7.fasta
Description

UniProtKB Summary for C2CD4A
Function: May be involved in inflammatory process. May regulate cell architecture and adhesion

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=C2CD4A ]
External IDs
Hgnc ID: 33627 EntrezGene ID: 145741 Ensembl ID: ENSG00000198535
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=C2CD4A ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
15527968NLF1 may play a role in regulating genes which control cellular architecture.2010-01-21
20818381Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)2010-09-15
20818381Single nucleotide polymorphism in C2CD4A is associated with type 2 diabetes.2010-10-30
23522043An endoplasmic reticulum protein, NLF-1, delivers a sodium leak channel critical for rhythmic locomotion.2013-05-18
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalianC2C4A_HUMANC2C4A_BOVIN3699762.8926.2921236119201145E-22102
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/Q8NCU7_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
No results found.
Evidence File
/mnt/mpp/ms_data/Q8NCU7_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q8NCU7_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB