ADGB:Androglobin

Gene Name
Androglobin
Protein ID
Q8N7X0
Chromosome ID
6
HPP Status
1
Protein Name
Androglobin
Synonyms

C6orf103

chromosome 6 open reading frame 103

androglobin

calpain-7-like protein

Calpain-7-like protein

CAPN7L


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=ADGB ]
Chromosomal Position
6q24.3 | Start:146598965 End:146598965
Sequence
Q8N7X0.fasta
Description

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=ADGB ]
External IDs
Hgnc ID: 21212 EntrezGene ID: 79747 Ensembl ID: ENSG00000118492
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=ADGB ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
22115833Molecular evolutionary analyses indicate that this chimeric globin family is phylogenetically ancient and originated in the common ancestor to animals and choanoflagellates. In humans and mice, the gene is predominantly expressed in testis tissue.2012-09-22
24966926Suggest ADGB is involved in the progression of glioma in vitro.2015-02-28
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalianADGB_HUMANADGB_MOUSE1667167473.36100.4240510116591164802360
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
ADGB_HUMANIPR001300GO:0004198DomainPeptidase C2, calpain, catalytic domainMolecular Functioncalcium-dependent cysteine-type endopeptidase activity
ADGB_HUMANIPR001300GO:0005622DomainPeptidase C2, calpain, catalytic domainCellular Componentintracellular
ADGB_HUMANIPR001300GO:0006508DomainPeptidase C2, calpain, catalytic domainBiological Processproteolysis
ADGB_HUMANIPR012292GO:0005506DomainGlobin, structural domainMolecular Functioniron ion binding
ADGB_HUMANIPR012292GO:0015671DomainGlobin, structural domainBiological Processoxygen transport
ADGB_HUMANIPR012292GO:0019825DomainGlobin, structural domainMolecular Functionoxygen binding
ADGB_HUMANIPR012292GO:0020037DomainGlobin, structural domainMolecular Functionheme binding
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




MaxQB

Evidence File
/mnt/mpp/ms_data/Q8N7X0_maxqb.txt
Reference
Christoph Schaab, Tamar Geiger, Gabriele Stoehr, Juergen Cox and Matthias Mann: "Analysis of high-accuracy, quantitative proteomics data in the MaxQB database", Mol Cell Proteomics 11 (2012) M111.014068.
http://maxqb.biochem.mpg.de/mxdb/ ">MaxQB


Showing 1-2 of 2 items.

PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
LLEAEHLK36.03,Mascot:score;0.00429070293034188,Mascot:expectation;PXD000447_31039_149218_Q8N7X0_LLEAEHLKPXD000447;PRIDE_Exp_Complete_Ac_31039.xml;spectrum=149218
LLEAEHLK35.33,Mascot:score;0.00504113638183055,Mascot:expectation;PXD000442_31013_3225_Q8N7X0_LLEAEHLKPXD000442;PRIDE_Exp_Complete_Ac_31013.xml;spectrum=3225
Evidence File
/mnt/mpp/ms_data/Q8N7X0_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Showing 1-2 of 2 items.

Proteomics DB

Peptide SequenceSearch EngineScoreThreshold ScoreIdentification IDExperiment IDAnnotation
ENISVADTLQKMaxquant131.820184972201
LLEAEHLKMaxquant117.170742715935109
Evidence File
/mnt/mpp/ms_data/Q8N7X0_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB