OTOP1:Otopetrin-1

Gene Name
Otopetrin-1
Protein ID
Q7RTM1
Chromosome ID
4
HPP Status
2
Protein Name
Otopetrin-1
Synonyms

otopetrin 1

otopetrin-1


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=OTOP1 ]
Chromosomal Position
4p16.3 | Start:4188803 End:4188803
Sequence
Q7RTM1.fasta
Description

UniProtKB Summary for OTOP1
Function: Required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP (By similarity)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=OTOP1 ]
External IDs
Hgnc ID: 19656 EntrezGene ID: 133060 Ensembl ID: ENSG00000163982
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=OTOP1 ]
Reference Source
http://www.nextprot.org

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalian with experimental evidenceOTOP1_HUMANOTOP1_MOUSE61256280.4391.83100251612496000757
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/Q7RTM1_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


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Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q7RTM1_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB