FRG2:Protein FRG2

Gene Name
Protein FRG2
Protein ID
Q64ET8
Chromosome ID
4
HPP Status
2
Protein Name
Protein FRG2
Synonyms

protein FRG2

FRG2A

FSHD region gene 2

FSHD region gene 2 protein


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=FRG2 ]
Chromosomal Position
4q35.2 | Start:190024351 End:190024351
Sequence
Q64ET8.fasta
Description

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=FRG2 ]
External IDs
Hgnc ID: 19136 EntrezGene ID: 448831 Ensembl ID: ENSG00000205097
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=FRG2 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
15520407FRG2 is upregulated in differentiating myoblast cultures of autosomal dominant facioscapulohumeral muscular dystrophy patients.2010-01-21
20975055Clinically, patients with FSHD2 are indistinguishable from patients with FSHD1. The present data suggest that FSHD1 and FSHD2 are the result of the same pathophysiologic process.2010-11-13
21695143new insights into the gene deregulation characterizing both FSHD-1 and FSHD-2, in which miRNAs may play a role2011-10-22
25256356Study showed that the variability in clinical severity of facioscapulohumeral muscular dystrophy in FSHD1 and FSHD2 individuals is dependent on individual differences in susceptibility to D4Z4 hypomethylation.2015-07-25
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
All Reviewed HumanFRG2_HUMANFRG2_HUMAN27827810010000127812781.00E-156548
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/Q64ET8_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q64ET8_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB