TECTB:Beta-tectorin

Gene Name
Beta-tectorin
Protein ID
Q96PL2
Chromosome ID
10
HPP Status
2
Protein Name
Beta-tectorin
Synonyms

tectorin beta

beta-tectorin


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=TECTB ]
Chromosomal Position
10q25.2 | Start:112283735 End:112283735
Sequence
Q96PL2.fasta
Description

Entrez Gene Summary for TECTB
This gene encodes a non-collagenous glycoprotein component of the tectorial membrane, which covers the auditory hair cells in the cochlea of the inner ear. A similar protein in mouse functions in low-frequency hearing. (provided by RefSeq, Jul 2013)

UniProtKB Summary for TECTB
Function: One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=TECTB ]
External IDs
Hgnc ID: 11721 EntrezGene ID: 6975 Ensembl ID: ENSG00000119913
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=TECTB ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
16385451Observational study of gene-disease association. (HuGE Navigator)2009-12-02
20379614Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)2010-06-30
22544735CEACAM16 can probably form higher order structures with other tectorial membrane proteins such as alpha-tectorin and beta-tectorin and influences the physical properties of the tectorial membrane2012-09-22
22673945Single nucleotide polymorphism in the ultraconserved elements of TECTB gene is associated with recurrence in colorectal adenocarcinoma.2013-02-09
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation



Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/Q96PL2_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
No results found.
Evidence File
/mnt/mpp/ms_data/Q96PL2_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Proteomics DB

Evidence File
/mnt/mpp/ms_data/Q96PL2_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB