SOX21:Transcription factor SOX-21

Gene Name
Transcription factor SOX-21
Protein ID
Q9Y651
Chromosome ID
13
HPP Status
1
Protein Name
Transcription factor SOX-21
Synonyms

SOX25

SOX-A

SOXA

transcription factor SOX-21

SRY-box 21

SRY (sex determining region Y)-box 21

"SRY-box 21"


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=SOX21 ]
Chromosomal Position
13q32.1 | Start:94709622 End:94709622
Sequence
Q9Y651.fasta
Description

Entrez Gene Summary for SOX21
SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA-binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).(supplied by OMIM, Apr 2004)

UniProtKB Summary for SOX21
Function: May play a role as an activator of transcription of OPRM1 (By similarity)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=SOX21 ]
External IDs
Hgnc ID: 11197 EntrezGene ID: 11166 Ensembl ID: ENSG00000125285
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=SOX21 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
20824710suggest that Sox21 can negatively regulate Sox2 in glioma. Our findings imply that Sox2 and Sox21 may be interesting targets for the development of novel glioma therapy2011-07-09
23463365Tumors originating from glioma cells with an induced expression of Sox21 exhibited an increased formation of Sox2:Sox21 complexes and an upregulation of S100beta, CNPase and Tuj12013-09-14
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation



Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




Showing 1-20 of 112 items.

gpmDB

Peptide SequenceEvidence LevelLog ENumber Of ObservationSpectraAccession IDProteotypicityAnnotation
VFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKgreen-15.0411ENSP00000366144Proteotypic
VFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKgreen-15.0411ENSP00000366144Proteotypic
VFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKgreen-15.0411ENSP00000366144Proteotypic
VFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKgreen-15.0411ENSP00000366144Proteotypic
VFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKgreen-14.8411ENSP00000366144Proteotypic
VFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKgreen-14.8411ENSP00000366144Proteotypic
AGAGLHAGAGGGLVPESLLANPEKgreen-11.8521ENSP00000366144Proteotypic
AGAGLHAGAGGGLVPESLLANPEKgreen-11.8521ENSP00000366144Proteotypic
AAAAAAAAAARVFFPQSAAAAAAAAAAAAAGgreen-11.4241ENSP00000366144Proteotypic
AAAAAAAAAARVFFPQSAAAAAAAAAAAAAGgreen-11.4241ENSP00000366144Proteotypic
FAFPVPYGLGGVADAEHPALKgreen-10.4191ENSP00000366144Proteotypic
FAFPVPYGLGGVADAEHPALKgreen-10.4191ENSP00000366144Proteotypic
PEKAAAAAAAAAARgreen-10.1481ENSP00000366144Proteotypic
PEKAAAAAAAAAARgreen-10.1481ENSP00000366144Proteotypic
FAFPVPYGLGGVADAEHPALKgreen-10.0191ENSP00000366144Proteotypic
FAFPVPYGLGGVADAEHPALKgreen-10.0191ENSP00000366144Proteotypic
AGAGLHAGAGGGLVPESLLANPEKgreen-9.4521ENSP00000366144Proteotypic
AGAGLHAGAGGGLVPESLLANPEKgreen-9.4521ENSP00000366144Proteotypic
FAFPVPYGLGGVADAEHPALKgreen-9.2191ENSP00000366144Proteotypic
FAFPVPYGLGGVADAEHPALKgreen-9.2191ENSP00000366144Proteotypic
Evidence File
/mnt/mpp/ms_data/Q9Y651_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
No results found.
Evidence File
/mnt/mpp/ms_data/Q9Y651_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Showing 1-1 of 1 item.

Proteomics DB

Peptide SequenceSearch EngineScoreThreshold ScoreIdentification IDExperiment IDAnnotation
RPMNAFMVWSRAQRMaxquant127.7901323463824-1
Evidence File
/mnt/mpp/ms_data/Q9Y651_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB