OXGR1:2-oxoglutarate receptor 1

Gene Name
2-oxoglutarate receptor 1
Protein ID
Q96P68
Chromosome ID
13
HPP Status
2
Protein Name
2-oxoglutarate receptor 1
Synonyms

P2Y15

P2RY15

G-protein coupled receptor 80

seven transmembrane helix receptor

Alpha-ketoglutarate receptor 1

P2Y-like nucleotide receptor

P2Y-like GPCR

G protein-coupled receptor 80

GPR99

alpha-ketoglutarate receptor 1

G-protein coupled receptor 99

GPR80

2-oxoglutarate receptor 1

G protein-coupled receptor 99

oxoglutarate receptor 1

P2Y purinoceptor 15

oxoglutarate (alpha-ketoglutarate) receptor 1


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=OXGR1 ]
Chromosomal Position
13q32.1 | Start:96985719 End:96985719
Sequence
Q96P68.fasta
Description

UniProtKB Summary for OXGR1
Function: Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway (By similarity)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=OXGR1 ]
External IDs
Hgnc ID: 4531 EntrezGene ID: 27199 Ensembl ID: ENSG00000165621
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=OXGR1 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
15001573P2Y15 is a cell surface receptor for AMP and adenosine2010-01-21
19760608Down-Regulation of OXGR1 through DNA Methylation is associated with hepatocellular carcinoma.2010-01-21
20379614Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)2010-06-30
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
OXGR1_HUMANIPR000276GO:0004930FamilyG protein-coupled receptor, rhodopsin-likeMolecular FunctionG-protein coupled receptor activity
OXGR1_HUMANIPR000276GO:0007186FamilyG protein-coupled receptor, rhodopsin-likeBiological ProcessG-protein coupled receptor signaling pathway
OXGR1_HUMANIPR000276GO:0016021FamilyG protein-coupled receptor, rhodopsin-likeCellular Componentintegral to membrane
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/Q96P68_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM