PCNXL2:Pecanex-like protein 2

Gene Name
Pecanex-like protein 2
Protein ID
A6NKB5
Chromosome ID
1
HPP Status
2
Protein Name
Pecanex-like protein 2
Synonyms

pecanex-like 2 (Drosophila)

KIAA0435

pecanex (Drosophila)-like 2

pecanex-like protein 2


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=PCNXL2 ]
Chromosomal Position
1q42.2 | Start:232983435 End:232983435
Sequence
A6NKB5.fasta
Description

UniProtKB Summary for PCNXL2
Function: May play a role in tumorigenesis of colorectal carcinomas with high microsatellite instability (MSI-H)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=PCNXL2 ]
External IDs
Hgnc ID: 8736 EntrezGene ID: 80003 Ensembl ID: ENSG00000135749
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=PCNXL2 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
12140758Identification of MARCKS, FLJ11383 and TAF1B as putative novel target genes in colorectal carcinomas with microsatellite instability.2010-01-21
19913121Observational study of gene-disease association. (HuGE Navigator)2010-09-15
20379614Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)2010-06-30
20628086Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)2010-09-15
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalian with experimental evidencePCX2_HUMANPCX3_MOUSE2137138754.0764.957616521188749418390.00E+001365
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
PCX2_HUMANIPR007735GO:0016021FamilyPecanexCellular Componentintegral to membrane
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/A6NKB5_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


Showing 1-3 of 3 items.

PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
NIWGGPITLDR29.81,Mascot:score;0.00198956762051684,Mascot:expectation;PXD001327_39776_18651_A6NKB5_NIWGGPITLDRPXD001327;ZR-75-1_cyt1_1.mgf;index=25510
NIWGGPITLDR0.00380035095166338,Mascot:expectation;26.44,Mascot:score;PXD001327_39774_994_A6NKB5_NIWGGPITLDRPXD001327;ZR-75-1_cyt1_2.mgf;index=60223
NIWGGPITLDR0.00380035095166338,Mascot:expectation;26.44,Mascot:score;PXD001327_39774_994_A6NKB5_NIWGGPITLDRPXD001327;ZR-75-1_cyt1_2.mgf;index=60223
Evidence File
/mnt/mpp/ms_data/A6NKB5_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Proteomics DB

Evidence File
/mnt/mpp/ms_data/A6NKB5_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB