FAM19A3:Protein FAM19A3

Gene Name
Protein FAM19A3
Protein ID
Q7Z5A8
Chromosome ID
1
HPP Status
2
Protein Name
Protein FAM19A3
Synonyms

chemokine-like protein TAFA-3

protein FAM19A3

family with sequence similarity 19 (chemokine (C-C motif)-like), member A3

Chemokine-like protein TAFA-3

TAFA-3

TAFA3


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=FAM19A3 ]
Chromosomal Position
1p13.2 | Start:112720419 End:112720419
Sequence
Q7Z5A8.fasta
Description

Entrez Gene Summary for FAM19A3
This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, Nov 2011)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=FAM19A3 ]
External IDs
Hgnc ID: 21590 EntrezGene ID: 284467 Ensembl ID: ENSG00000184599
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=FAM19A3 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
25595455FAM19A3 modulates the microglia/macrophage polarization dynamics and ameliorates cerebral ischemia.2015-04-18
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalianF19A3_HUMANF19A3_MOUSE13313187.0298.5170313321327E-52199
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/Q7Z5A8_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM