SIAH3:Seven in absentia homolog 3

Gene Name
Seven in absentia homolog 3
Protein ID
Q8IW03
Chromosome ID
13
HPP Status
2
Protein Name
Seven in absentia homolog 3
Synonyms

seven in absentia homolog 3 (Drosophila)

siah E3 ubiquitin protein ligase family member 3

Siah-3

siah-3

seven in absentia homolog 3


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=SIAH3 ]
Chromosomal Position
13q14.13 | Start:45777243 End:45777243
Sequence
Q8IW03.fasta
Description

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=SIAH3 ]
External IDs
Hgnc ID: 30553 EntrezGene ID: 283514 Ensembl ID: ENSG00000215475
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=SIAH3 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
20379614Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)2010-06-30
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation


Sequence Similarity

Db NameQuery UniSubject UniSequence LengthAlignment LengthIdentityCoverageMismatchesGap OpeningsQuery StartQuery EndSubject StartSubject EndEvalueBit Score
Reviewed non-human mammalian with experimental evidenceSIAH3_HUMANSIAH2_RAT26915656.4157.996711042581663211.00E-49192
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

InterProScan Annotation

Uniprot IDInterpro IDGo IDTypeNameCategoryDescription
SIAH3_HUMANIPR004162GO:0005634FamilySeven-in-absentia protein, sinaCellular Componentnucleus
SIAH3_HUMANIPR004162GO:0006511FamilySeven-in-absentia protein, sinaBiological Processubiquitin-dependent protein catabolic process
SIAH3_HUMANIPR004162GO:0007275FamilySeven-in-absentia protein, sinaBiological Processmulticellular organismal development
SIAH3_HUMANIPR008974GO:0005515DomainTRAF-likeMolecular Functionprotein binding
SIAH3_HUMANIPR018121GO:0005634DomainSeven-in-absentia protein, TRAF-like domainCellular Componentnucleus
SIAH3_HUMANIPR018121GO:0006511DomainSeven-in-absentia protein, TRAF-like domainBiological Processubiquitin-dependent protein catabolic process
SIAH3_HUMANIPR018121GO:0007275DomainSeven-in-absentia protein, TRAF-like domainBiological Processmulticellular organismal development
Reference
Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83.

Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
No results found.
Evidence File
/mnt/mpp/ms_data/Q8IW03_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive