MYO16:Unconventional myosin-XVI

Gene Name
Unconventional myosin-XVI
Protein ID
Q9Y6X6
Chromosome ID
13
HPP Status
1
Protein Name
Unconventional myosin-XVI
Synonyms

unconventional myosin-16

neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 3

Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3

neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3

Myo16b

MYAP3

KIAA0865

MYR8

myosin-XVI

myosin heavy chain Myr 8

MYO16B

myosin XVI

"neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 3"

Unconventional myosin-16

NYAP3

MYO16 variant protein

unconventional myosin-XVI


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=MYO16 ]
Chromosomal Position
13q33.3 | Start:108596152 End:108596152
Sequence
Q9Y6X6.fasta
Description

UniProtKB Summary for MYO16
Function: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development. Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis (By similarity)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=MYO16 ]
External IDs
Hgnc ID: 29822 EntrezGene ID: 23026 Ensembl ID: ENSG00000041515
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=MYO16 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
19913121Observational study of gene-disease association. (HuGE Navigator)2010-09-15
20201926Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)2010-04-07
20379614Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)2010-06-30
20628086Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)2010-09-15
24141571This study suggest that common variation within MYO16 may contribute to the genetic liability to schizophrenia.2014-10-11
25902260KIRREL3 interacting proteins MAP1B and MYO16 are potential candidates for intellectual disability and autism spectrum disorder.2016-04-16
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation



Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




Showing 1-20 of 24 items.

gpmDB

Peptide SequenceEvidence LevelLog ENumber Of ObservationSpectraAccession IDProteotypicityAnnotation
VMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLFQSKgreen-15.001ENSP00000350160Proteotypic
VMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLFQSKgreen-15.001ENSP00000401633Proteotypic
VMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLFQSKgreen-15.001ENSP00000349145Proteotypic
VMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLFQSKgreen-15.001ENSP00000350160Proteotypic
VMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLFQSKgreen-15.001ENSP00000401633Proteotypic
VMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLFQSKgreen-15.001ENSP00000349145Proteotypic
TYDALVIQNASDIARgreen-10.3171ENSP00000350160Proteotypic
TYDALVIQNASDIARgreen-10.3171ENSP00000349145Proteotypic
TYDALVIQNASDIARgreen-10.3171ENSP00000401633Proteotypic
TYDALVIQNASDIARgreen-10.3171ENSP00000350160Proteotypic
TYDALVIQNASDIARgreen-10.3171ENSP00000349145Proteotypic
TYDALVIQNASDIARgreen-10.3171ENSP00000401633Proteotypic
YLNQTIQDDASTGERgreen-6.5161ENSP00000350160Proteotypic
YLNQTIQDDASTGERgreen-6.5161ENSP00000349145Proteotypic
YLNQTIQDDASTGERgreen-6.5161ENSP00000251041Proteotypic
YLNQTIQDDASTGERgreen-6.5161ENSP00000401633Proteotypic
YLNQTIQDDASTGERgreen-6.5161ENSP00000350160Proteotypic
YLNQTIQDDASTGERgreen-6.5161ENSP00000349145Proteotypic
YLNQTIQDDASTGERgreen-6.5161ENSP00000251041Proteotypic
YLNQTIQDDASTGERgreen-6.5161ENSP00000401633Proteotypic
Evidence File
/mnt/mpp/ms_data/Q9Y6X6_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


Showing 1-1 of 1 item.

MaxQB

Peptide SequenceSearch EngineBest ScoreBest Evidence IDBest Raw File IDBest Msms ScanAnnotation
YPVQPEGSSPLSPQYSKMaxQuant180.68799071420120309_EXQ5_KiSh_SA_LabelFree_HeLa_Phospho_EGF_rep4_FT345491
Evidence File
/mnt/mpp/ms_data/Q9Y6X6_maxqb.txt
Reference
Christoph Schaab, Tamar Geiger, Gabriele Stoehr, Juergen Cox and Matthias Mann: "Analysis of high-accuracy, quantitative proteomics data in the MaxQB database", Mol Cell Proteomics 11 (2012) M111.014068.
http://maxqb.biochem.mpg.de/mxdb/ ">MaxQB


Showing 1-1 of 1 item.

PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
QQEVTSINSFLQNTEDMGLK0.00884626824521258,Mascot:expectation;21.89,Mascot:score;PXD000039_27349_27487_Q9Y6X6_QQEVTSINSFLQNTEDMGLKPXD000039;PRIDE_Exp_Complete_Ac_27349.xml;spectrum=27487
Evidence File
/mnt/mpp/ms_data/Q9Y6X6_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive