GLT6D1:Glycosyltransferase 6 domain-containing protein 1
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Gene Name
Glycosyltransferase 6 domain-containing protein 1 |
Protein ID
Q7Z4J2 |
Chromosome ID
9 |
HPP Status
2 |
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Protein Name
Glycosyltransferase 6 domain-containing protein 1 |
Synonyms
GT6M7 galactosyltransferase family 6 domain-containing 1 GLTDC1 galactosyltransferase family 6 domain containing 1 Galactosyltransferase family 6 domain-containing 1 glycosyltransferase 6 domain containing 1 glycosyltransferase 6 domain-containing protein 1 EC 2.4.1.- [Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=GLT6D1  ] |
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Chromosomal Position
9q34.3 | Start:135623656 End:135623656 |
Sequence
Q7Z4J2.fasta |
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Description
Entrez Gene Summary for GLT6D1The GT6 glycosyltransferases gene family, which includes the ABO blood group (ABO; MIM 110300) and GLT6D1, shows a complex evolution pattern, with multiple events of gain and loss in different mammal species. In humans, the ABO gene is considered the sole functional member, although the O allele is null and is fixed in certain populations (summary by Casals et al. (2009) (PubMed 19218399)).(supplied by OMIM, Jan 2011) [Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=GLT6D1 ] |
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External IDs
Hgnc ID: 23671 EntrezGene ID: 360203 Ensembl ID: ENSG00000204007 [Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=GLT6D1 ] |
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Reference Source
http://www.nextprot.org |
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Gene Reference Into Function (GeneRIF)
| PubMed ID | GeneRIF Text | Last Update |
|---|---|---|
| 19897590 | GLT6D1 is a susceptibility locus for periodontitis. | 2010-03-29 |
| 19897590 | Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | 2009-12-02 |
| 20800603 | Observational study of gene-disease association. (HuGE Navigator) | 2010-12-05 |
| Reference http://www.ncbi.nlm.nih.gov/gene/about-generif ftp://ftp.ncbi.nih.gov/gene/GeneRIF/ | ||
OMICSDI Browser
Relevant citations within the PubMed literature
Putative/known Functions
Localisation
Homologues, Orthologues, Paralogues and Family
Sequence Similarity and Functional Annotation
Sequence Similarity
| Db Name | Query Uni | Subject Uni | Sequence Length | Alignment Length | Identity | Coverage | Mismatches | Gap Openings | Query Start | Query End | Subject Start | Subject End | Evalue | Bit Score |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Reviewed non-human mammalian with experimental evidence | GL6D1_HUMAN | GGTA1_BOVIN | 308 | 289 | 53.98 | 93.83 | 131 | 1 | 20 | 306 | 72 | 360 | 1E-89 | 325 |
| Reference Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83. | ||||||||||||||
InterProScan Annotation
| Uniprot ID | Interpro ID | Go ID | Type | Name | Category | Description |
|---|---|---|---|---|---|---|
| GL6D1_HUMAN | IPR005076 | GO:0005975 | Family | Glycosyl transferase, family 6 | Biological Process | carbohydrate metabolic process |
| GL6D1_HUMAN | IPR005076 | GO:0016020 | Family | Glycosyl transferase, family 6 | Cellular Component | membrane |
| Reference Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83. | ||||||