CACNG6:Voltage-dependent calcium channel gamma-6 subunit

Gene Name
Voltage-dependent calcium channel gamma-6 subunit
Protein ID
Q9BXT2
Chromosome ID
19
HPP Status
2
Protein Name
Voltage-dependent calcium channel gamma-6 subunit
Synonyms

neuronal voltage-gated calcium channel gamma-6 subunit

calcium channel, voltage-dependent, gamma subunit 6

voltage-dependent calcium channel gamma-6 subunit

Neuronal voltage-gated calcium channel gamma-6 subunit


[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=CACNG6 ]
Chromosomal Position
19q13.42 | Start:53992288 End:53992288
Sequence
Q9BXT2.fasta
Description

Entrez Gene Summary for CACNG6
Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). Alternative splicing results in multiple transcript variants. Variants in this gene have been associated with aspirin-intolerant asthma. (provided by RefSeq, Dec 2010)

UniProtKB Summary for CACNG6
Function: Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity)

[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=CACNG6 ]
External IDs
Hgnc ID: 13625 EntrezGene ID: 59285 Ensembl ID: ENSG00000130433
[Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=CACNG6 ]
Reference Source
http://www.nextprot.org

Gene Reference Into Function (GeneRIF)


PubMed IDGeneRIF TextLast Update
20860846CACNG6 variants might be associated with the risk of aspirin-intolerant asthma in a Korean population.2010-10-30
20860846Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)2010-12-05
Reference
http://www.ncbi.nlm.nih.gov/gene/about-generif
ftp://ftp.ncbi.nih.gov/gene/GeneRIF/

OMICSDI Browser



Relevant citations within the PubMed literature

         

Putative/known Functions



Localisation



Homologues, Orthologues, Paralogues and Family



Sequence Similarity and Functional Annotation



Post Translational Modifications



Protein Protein Interactions



Best Available Mass Spectra without FDR




gpmDB

Evidence File
/mnt/mpp/ms_data/Q9BXT2_gpmdb.txt
Reference
Fenyö, David; Beavis, Ronald C. (2015). "The GPMDB REST interface". Bioinformatics 31 (12): 2056–2058. doi:10.1093/bioinformatics/btv107. ISSN 1367-4803.
http://gpmdb.thegpm.org/ ">Global Proteome Machine Database - THE GPM


Showing 41-42 of 42 items.

PRIDE

Peptide SequenceScoresPride IDSpectrum IDAnnotation
GAEFLLR37.2,Mascot:score;0.0133668069365122,Mascot:expectation;PXD000443_31019_480734_Q9BXT2_GAEFLLRPXD000443;PRIDE_Exp_Complete_Ac_31019.xml;spectrum=480734
GAEFLLR37.2,Mascot:score;0.0133668069365122,Mascot:expectation;PXD000443_31019_480734_Q9BXT2_GAEFLLRPXD000443;PRIDE_Exp_Complete_Ac_31019.xml;spectrum=480734
Evidence File
/mnt/mpp/ms_data/Q9BXT2_pridedb.txt
Reference
Vizcaino JA, et al. 2016 update of the PRIDE database and related tools. Nucleic Acids Res. 2016 Jan 1;44(D1):D447-D456.
https://www.ebi.ac.uk/pride/archive/ ">PRIDE Archive


Showing 1-6 of 6 items.

Proteomics DB

Peptide SequenceSearch EngineScoreThreshold ScoreIdentification IDExperiment IDAnnotation
GAEFLLRMaxquant188.45012160916172995
GAEFLLRMaxquant173.930610591005
GAEFLLRMaxquant154.0901275214839-1
GAEFLLRMaxquant150.0201350965868-1
GAEFLLRMaxquant145.040535446489161
GAEFLLRMaxquant118.01054568240138
Evidence File
/mnt/mpp/ms_data/Q9BXT2_protdb.txt
Reference
Wilhelm, M et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature. 509:582-7.
https://www.proteomicsdb.org/ ">Proteomics DB