FBXO16:F-box only protein 16
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Gene Name
F-box only protein 16 |
Protein ID
Q8IX29 |
Chromosome ID
8 |
HPP Status
2 |
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Protein Name
F-box only protein 16 |
Synonyms
F-box protein 16 F-box only protein 16 F-box only protein 16 FBX16 [Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=FBXO16  ] |
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Chromosomal Position
8p21.1 | Start:28348287 End:28348287 |
Sequence
Q8IX29.fasta |
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Description
Entrez Gene Summary for FBXO16This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Apr 2012) UniProtKB Summary for FBXO16Function: Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation [Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=FBXO16 ] |
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External IDs
Hgnc ID: 13618 EntrezGene ID: 157574 Ensembl ID: ENSG00000214050 [Reference: http://www.genecards.org/cgi-bin/carddisp.pl?gene=FBXO16 ] |
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Reference Source
http://www.nextprot.org |
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Gene Reference Into Function (GeneRIF)
| PubMed ID | GeneRIF Text | Last Update |
|---|---|---|
| 12243353 | FBXO16 was localized to the human chromosome 8p12. The FBXO16 gene consisted of 9 exons that spanned 67,816 bp of human genomic DNA | 2010-01-21 |
| Reference http://www.ncbi.nlm.nih.gov/gene/about-generif ftp://ftp.ncbi.nih.gov/gene/GeneRIF/ | ||
OMICSDI Browser
Relevant citations within the PubMed literature
Putative/known Functions
Localisation
Homologues, Orthologues, Paralogues and Family
Sequence Similarity and Functional Annotation
InterProScan Annotation
| Uniprot ID | Interpro ID | Go ID | Type | Name | Category | Description |
|---|---|---|---|---|---|---|
| FBX16_HUMAN | IPR001810 | GO:0005515 | Domain | F-box domain | Molecular Function | protein binding |
| Reference Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S (2014) Protannotator: A Semiautomated Pipeline for Chromosome-Wise Functional Annotation of the "Missing" Human Proteome. J Proteome Res. 13, 76-83. | ||||||